Skip to main content

Table 4 Adjusted Cox regression (Model 1) of the combined contributions of kynurenic acid and neopterin in stroke, mortality and the composite endpoint (stroke and death)

From: Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke

  Stroke recurrence Death Stroke and death
  HR CI p HR CI p HR CI p
KA 0.78 (0.39, 1.57) 0.492 0.57 (0.33, 0.97) 0.038 0.72 (0.46, 1.10) 0.131
Neopterin 1.48 (0.83, 1.57) 0.177 1.61 (1.02, 2.54) 0.040 1.59 (1.11, 2.27) 0.011
Age 0.98 (0.51, 2.61) 0.949 1.11 (0.60, 2.06) 0.746 1.09 (0.68, 1.76) 0.720
Sex 1.39 (0.73, 2.66) 0.314 1.61 (1.00, 2.62) 0.052 1.43 (0.97, 2.10) 0.071
Prior CeVD 1.37 (0.87, 2.17) 0.175 1.56 (1.10, 2.22) 0.012 1.44 (1.08, 1.91) 0.012
mRS 0.97 (0.46, 2.05) 0.945 3.25 (1.77, 5.96) < 0.001 2.24 (1.40, 3.57) 0.001
Creatinine 1.31 (0.20, 3.38) 0.583 2.23 (1.12, 4.42) 0.022 1.65 (0.93, 2.92) 0.085
  1. The analyses includes KA, neopterin and Model 1: Age, sex, prior cerebrovascular disease, modified Rankin Scale at three months, creatinine
  2. HR = hazard ratio. CI = confidence interval. KA = kynurenic acid. CeVD = cerebrovascular disease. mRS = modified Rankin Scale