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Table 1 Clinical characteristics of three patients with Holmes tremor

From: Study on the pathogenesis of Holmes tremor by multimodal 3D medical imaging: case reports of three patients

Patient

Gender

Age of Onset

Delay in HT Onset Time (Months)

Past Medical History

Etiology

Lesion Location

Side of Tremor

Limb with Tremor

Hemiplegia

Aphasia

Paresthesia

Involvement of Oculomotor Nucleus

Treatment Method, Remission Degree and Duration

Case 1

Female

73

12

Hypertension for 2+ years

HICH

Left thalamus

Right

Upper + lower limbs

Yes

None

None

None

The symptoms disappeared 1 month after treatment with 2 mg clonazepam Tablets (qd po).

Case 2

Female

23

2

None

AVM

Left thalamus

Right

Upper + lower limbs

None

None

None

None

pramipexole 0.375 mg/d,

20%, 1 month

Case 3

Male

71

0.5

Hypertension

2 years

HICH

Right thalamus

Left

Upper limbs

Yes

None

None

Yes

pramipexole 0.375 mg/d,

80%, 1 month

  1. Note: HICH hypertensive cerebral hemorrhage, AVM arteriovenous malformation