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Fig. 3 | BMC Neurology

Fig. 3

From: An autopsied case report of spastic paraplegia with thin corpus callosum carrying a novel mutation in the SPG11 gene: widespread degeneration with eosinophilic inclusions

Fig. 3

Macroscopic findings. A The brain was small overall. B In a sagittal section of the cerebrum, a thin corpus callosum and frontal lobe atrophy were observed. C In a coronal section, a thin corpus callosum, mild enlargement of the anterior horn of the lateral ventricle (resulting from decreased cerebral cortex and white matter volumes), and a mildly atrophic thalamus were observed. D, E The brainstem was small at all levels, and the substantia nigra and locus coeruleus were depigmented. Scale bars: 2 cm (A, B); 1 cm (C); 5 mm (D, E)

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