An autopsied case report of spastic paraplegia with thin corpus callosum carrying a novel mutation in the SPG11 gene: widespread degeneration with eosinophilic inclusions

Table 2 Clinical characteristics of autopsied patients with hereditary spastic paraplegia with a thin corpus callosum and mutations in SPG11

Patient	Sex	Mutation of the SPG11 gene	Age at death (years)	Age at onset of motor symptoms (years)	Time from motor symptom onset to clinical event (years)
Patient	Sex	Mutation of the SPG11 gene	Age at death (years)	Age at onset of motor symptoms (years)	Bedridden	Need for artificial ventilation	Death
Patient in Kuru, et al. (2005)	Male	#1 not examined in the patient	51	14	23	36	37
Patient 1 in Denora, et al. (2016)	Female	#2 in patient herself	32	12	Not described	Not needed	20
Patient 2 in Denora, et al. (2016)	Female	#3 not examined in the patient	46	10	< 35	Not needed	36
Patient 1 in Mori, et al. (2021)	Female	#4 in patient herself	57	25	15	Not needed	32
Present patient	Male	#5 in patient himself	44	13	12	13	31

ISSN: 1471-2377