Total SVD Score
|
All Patients
(n = 308)
|
Dysphagia
(n = 54)
|
Controls
(n = 254)
|
χ2
|
P
|
---|
0
|
73(23.70)
|
6(11.11)
|
67(26.38)
|
5.74
|
0.02
|
1
|
115(37.34)
|
7(12.96)
|
108(42.52)
|
16.63
|
< 1.00 × 10− 3*
|
2
|
73(23.70)
|
16(29.63)
|
57(22.44)
|
1.27
|
0.26
|
3
|
37(12.01)
|
17(31.48)
|
20(7.87)
|
23.48
|
< 1.00 × 10−3*
|
4
|
10(3.25)
|
8(14.82)
|
2(0.79)
|
27.89
|
< 1.00 × 10−3*
|
- *: p < 0.001
- SVD refers to small vessel disease. On brain magnetic resonance imaging, we independently rated the presence of cerebral microbleeds, lacunes, white matter hyperintensities and enlarged perivascular spaces. The presence of each SVD feature was summed in the total SVD score ranging from 0 to 4. Data presented as number (%). Categorical data differences in patients and controls are represented with statistical significance based on chi-squared test (χ2 & p). Mann–Whitney test of dysphagia patients vs. Controls in Single-RSSI patients, Z = − 6.29, p < 1.00 × 10− 3