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Table 1 The demographic, clinical characteristic and alertness of two groups with TLE and HCs

From: A study of brain functional network and alertness changes in temporal lobe epilepsy with and without focal to bilateral tonic–clonic seizures

 

TLE-non-FBTCS (18)

TLE- FBTCS

(21)

Health control

(22)

P value

Gender (M/F)

8/10

11/10

9/13

0.744(Chi-square)

Age (M ± SD)

29.722 ± 8.857

33.523 ± 8.376

29.772 ± 6.279

0.212(ANOVA)

Education years, median (range)

15(9-16)

12(9-16)

15(10-18)

0.103(Kruskal-Wallis)

Side (R/L)

11/7

11/10

/

0.584(Chi-square)

Hippocampal sclerosis (Yes or No)

8/10

12/9

/

0.429(Chi-square)

Age of epilepsy onset (M ± SD)

21.278 ± 10.665

21.238 ± 11.144

/

0.991(T-test)

Number of seizure years, median (range)

5.5(1-21)

11.0(3-35)

/

0.068 (Mann-Whitney)

Type of seizure

FAS

5

/

/

/

FIAS

10

/

/

/

FAS + FIAS

3

/

/

/

FAS + FBTCS

/

2

/

/

FIAS+FBTCS

/

19

/

/

Alertness

Alertness effect (M ± SD)

0.106 ± 0.037

0.078 ± 0.034

0.090 ± 0.033

0.043(ANOVA)

No cue RT (M ± SD) ms

669.49 ± 87.15

715.87 ± 129.06

606.29 ± 72.22

0.003(Kruskal-Wallis)

Double cue RT median (range)ms

616.32 (455.52-746.40)

701.68 (569.89-1085.79)

547.76 (457.38-708.38)

0.003(Kruskal-Wallis)

ASM (mono or polytherapy)

5/13

7/14

/

0.708(Chi-square)

  1. HCs Health controls, M Man, F Female, M ± SD Mean ± standard deviation, ASM Anti-seizure medications, FAS Focal aware seizures, FIAS Focal impaired awareness seizures, FBTCS Focal to bilateral tonic–clonic seizures, ANOVA One-way analysis of variance, χ2 Chi-square tests; NA