Table 1 Baseline patient characteristics

Gender: male, number (%)

49 (60)

9 (90)

44 (94)

18 (90)

Age (years)

38 (31–46)

41 (35–46)

40 (34–45)

45 (38–52)

CD4+ T-cell count (×  106 cells/L)

210 (70–330)

68 (60–137)

90 (17–175)

49 (38–52)

CD4+ nadir T-cell count (× 106 cells/L)

180 (60–250)

52 (16–80)

141 (18–160)c

65 (50–130)e

Plasma HIV RNA (log10 copies/mL)

4.79 (4.32–5.42)

5.49 (5.32–5.78)

4.87 (1.72–5.50)

<  1.70

CSF HIV RNA (log10 copies/mL)

3.78 (3.23–4.38)

5.23 (5.09–5.41)

4.16 (2.78–4.98)

<  1.70

Albumin ratio

4.26 (3.57–6.00)

10.6 (7.50–17.24)

9.90 (5.72–13.23)

6.57 (4.87–7.36)

CSF neopterin (nmol/L)

18.1 (11.5–24.0)

50.4 (43.1–85.8)a

50.0 (27.2–95.5)

13.5 (9.6–17.9)

CSF NfL (ng/L)

422 (318–713)

14,115 (9824–23,543)b

9731 (7603–21,555)d

f

Follow-up, days

758 (230–1752)

241 (50–994)

N/A

N/A