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Table 2 Multivariate Cox analysis using ACCI as a categorical variable as well as in dichotomised form

From: Age-adjusted Charlson comorbidity index in recurrent glioblastoma: a new prognostic factor?

 

Hazard Ratio

95% CI

P-Value

Age (> = 65 vs. < 65)

0.62

0.34–1.13

0.12

Postoperative KPSS (< 80 vs. > = 80)*

2.00

1.25–3.22

0.004

Resection (complete/incomplete)

1.61

1.04–2.51

0.034

ACCI

0.94

0.80–1.11

0.467

A

 Age (> = 65 vs. < 65)

0.74

0.41–1.32

0.306

 ACCI

0.98

0.84–1.15

0.84

 Resection (complete/incomplete) *

1.74

1.12–2.67

0.013

B

 Age (> = 65 vs. < 65)

0.80

0.50–1.29

0.363

 Resection (complete/incomplete) *

1.83

1.17–2.85

0.008

 ACCI 6.5

0.64

0.31–1.31

0.219

C

 Age (> = 65 vs. < 65)

0.75

0.46–1.21

0.236

 Resection (complete/incomplete) *

1.68

1.07–2.64

0.023

 ACCI 6.5

0.71

0.34–1.48

0.359

 Postoperative KPS (< 80 vs. > = 80)*

1.88

1.18–3.01

0.008

  1. CI Confidence Interval; *P</=0.05
  2. A Subanalysis without KPSS; B Subanalysis with the ACCI cut-off of 6.5; C Subanalysis with the ACCI cut-off of 6.5 and KPSS