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Table 1 Characteristics of the study cohort

From: COVID-19 related outcomes among individuals with neurodegenerative diseases: a cohort analysis in the UK biobank

Characteristics Individuals with neurodegenerative diseases (n = 2617) Individuals without neurodegenerative diseases (n = 93,658) Total (n = 96,275)
Mean age (SD) at outbreaka, years 74.2 (5.84) 67.7 (8.23) 67.9 (8.25)
Age group, years
  ≤ 66 187 (7.1) 30,254 (32.3) 30,441 (31.6)
 67–75 436 (16.7) 26,367 (28.2) 26,803 (27.8)
  ≥ 76 1994 (76.2) 37,037 (39.5) 39,031 (40.5)
Sex
 Female 1230 (47.0) 50,369 (53.8) 51,599 (53.6)
 Male 1387 (53.0) 43,289 (46.2) 44,676 (46.4)
Race/ethnicity
 White 2407 (92.0) 83,989 (89.7) 86,396 (89.7)
 Other 189 (7.2) 9136 (9.8) 9325 (9.7)
 Unknown 21 (0.8) 533 (0.6) 554 (0.6)
Body mass index, kg/m2
  < 24.9 696 (26.6) 27,367 (29.2) 28,063 (29.1)
 24.9–29.9 1082 (41.3) 39,782 (42.5) 40,864 (42.4)
  ≥ 30 797 (30.5) 25,885 (27.6) 26,682 (27.7)
 Unknown 42 (1.6) 624 (0.7) 666 (0.7)
Smoking
 Never 1287 (49.2) 48,823 (52.1) 50,110 (52.0)
 Ever 1296 (49.5) 44,200 (47.2) 45,496 (47.3)
 Unknown 34 (1.3) 635 (0.7) 669 (0.7)
Alcohol use
 Never 176 (6.7) 4420 (4.7) 4596 (4.8)
 Previous 182 (7.0) 3534 (3.8) 3716 (3.9)
 Current 2237 (85.5) 85,364 (91.1) 87,601 (91.0)
 Unknown 22 (0.8) 340 (0.4) 362 (0.4)
Townsend deprivation index −0.74 (3.41) −1.20 (3.12) −1.19 (3.13)
Annual household income, £
  < 18,000 909 (34.7) 18,534 (19.8) 19,443 (20.2)
 18,000-30,999 556 (21.2) 19,911 (21.3) 20,467 (21.3)
 31,000-51,999 290 (11.1) 20,358 (21.7) 20,648 (21.4)
 52,000-100,000 168 (6.4) 15,601 (16.7) 15,769 (16.4)
  > 100,000 50 (1.9) 4577 (4.9) 4627 (4.8)
 Unknown 644 (24.6) 14,677 (15.7) 15,321 (15.9)
Educational attainment
 College or University degree 544 (20.8) 28,109 (30.0) 28,653 (29.8)
 A levels/AS levels or equivalent 198 (7.6) 9953 (10.6) 10,151 (10.5)
 O levels/GCSEs or equivalent 491 (18.8) 19,969 (21.3) 20,460 (21.3)
 CSEs or equivalent 72 (2.8) 5545 (5.9) 5617 (5.8)
 NVQ or HND or HNC or equivalent 187 (7.1) 6550 (7.0) 6737 (7.0)
 Other professional qualifications 158 (6.0) 4964 (5.3) 5122 (5.3)
 Unknown 967 (37.0) 18,568 (19.8) 19,535 (20.3)
Charlson Comorbidity Index 2.62 (2.78) 1.29 (2.16) 1.32 (2.19)
Any COVID-19
 Yes 718 (27.4) 17,220 (18.4) 17,938 (18.6)
 No 1899 (72.6) 76,438 (81.6) 78,337 (81.4)
Inpatient COVID-19
 Yes 379 (14.5) 5370 (5.7) 5749 (6.0)
 No 2238 (85.5) 88,288 (94.3) 90,526 (94.0)
COVID-19 related death
 Yes 195 (7.5) 986 (1.1) 1181 (1.2)
 No 2422 (92.5) 92,672 (98.9) 95,094 (98.8)
  1. Data are n/N (%), unless otherwise specified
  2. aThe first case of COVID-19 was diagnosed on January 31st 2020 in the UK
  3. Any COVID-19 includes a positive test result of COVID-19 according to Public Health England, an inpatient diagnosis from UK Biobank inpatient hospital data, or a death related to COVID-19