Table 1 Characteristics of the study cohort
Characteristics | Individuals with neurodegenerative diseases (n = 2617) | Individuals without neurodegenerative diseases (n = 93,658) | Total (n = 96,275) |
|---|---|---|---|
Mean age (SD) at outbreaka, years | 74.2 (5.84) | 67.7 (8.23) | 67.9 (8.25) |
Age group, years | |||
  ≤ 66 | 187 (7.1) | 30,254 (32.3) | 30,441 (31.6) |
 67–75 | 436 (16.7) | 26,367 (28.2) | 26,803 (27.8) |
  ≥ 76 | 1994 (76.2) | 37,037 (39.5) | 39,031 (40.5) |
Sex | |||
 Female | 1230 (47.0) | 50,369 (53.8) | 51,599 (53.6) |
 Male | 1387 (53.0) | 43,289 (46.2) | 44,676 (46.4) |
Race/ethnicity | |||
 White | 2407 (92.0) | 83,989 (89.7) | 86,396 (89.7) |
 Other | 189 (7.2) | 9136 (9.8) | 9325 (9.7) |
 Unknown | 21 (0.8) | 533 (0.6) | 554 (0.6) |
Body mass index, kg/m2 | |||
  < 24.9 | 696 (26.6) | 27,367 (29.2) | 28,063 (29.1) |
 24.9–29.9 | 1082 (41.3) | 39,782 (42.5) | 40,864 (42.4) |
  ≥ 30 | 797 (30.5) | 25,885 (27.6) | 26,682 (27.7) |
 Unknown | 42 (1.6) | 624 (0.7) | 666 (0.7) |
Smoking | |||
 Never | 1287 (49.2) | 48,823 (52.1) | 50,110 (52.0) |
 Ever | 1296 (49.5) | 44,200 (47.2) | 45,496 (47.3) |
 Unknown | 34 (1.3) | 635 (0.7) | 669 (0.7) |
Alcohol use | |||
 Never | 176 (6.7) | 4420 (4.7) | 4596 (4.8) |
 Previous | 182 (7.0) | 3534 (3.8) | 3716 (3.9) |
 Current | 2237 (85.5) | 85,364 (91.1) | 87,601 (91.0) |
 Unknown | 22 (0.8) | 340 (0.4) | 362 (0.4) |
Townsend deprivation index | −0.74 (3.41) | −1.20 (3.12) | −1.19 (3.13) |
Annual household income, £ | |||
  < 18,000 | 909 (34.7) | 18,534 (19.8) | 19,443 (20.2) |
 18,000-30,999 | 556 (21.2) | 19,911 (21.3) | 20,467 (21.3) |
 31,000-51,999 | 290 (11.1) | 20,358 (21.7) | 20,648 (21.4) |
 52,000-100,000 | 168 (6.4) | 15,601 (16.7) | 15,769 (16.4) |
  > 100,000 | 50 (1.9) | 4577 (4.9) | 4627 (4.8) |
 Unknown | 644 (24.6) | 14,677 (15.7) | 15,321 (15.9) |
Educational attainment | |||
 College or University degree | 544 (20.8) | 28,109 (30.0) | 28,653 (29.8) |
 A levels/AS levels or equivalent | 198 (7.6) | 9953 (10.6) | 10,151 (10.5) |
 O levels/GCSEs or equivalent | 491 (18.8) | 19,969 (21.3) | 20,460 (21.3) |
 CSEs or equivalent | 72 (2.8) | 5545 (5.9) | 5617 (5.8) |
 NVQ or HND or HNC or equivalent | 187 (7.1) | 6550 (7.0) | 6737 (7.0) |
 Other professional qualifications | 158 (6.0) | 4964 (5.3) | 5122 (5.3) |
 Unknown | 967 (37.0) | 18,568 (19.8) | 19,535 (20.3) |
Charlson Comorbidity Index | 2.62 (2.78) | 1.29 (2.16) | 1.32 (2.19) |
Any COVID-19 | |||
 Yes | 718 (27.4) | 17,220 (18.4) | 17,938 (18.6) |
 No | 1899 (72.6) | 76,438 (81.6) | 78,337 (81.4) |
Inpatient COVID-19 | |||
 Yes | 379 (14.5) | 5370 (5.7) | 5749 (6.0) |
 No | 2238 (85.5) | 88,288 (94.3) | 90,526 (94.0) |
COVID-19 related death | |||
 Yes | 195 (7.5) | 986 (1.1) | 1181 (1.2) |
 No | 2422 (92.5) | 92,672 (98.9) | 95,094 (98.8) |