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Table 4 Individuals with any or specific neurodegenerative disease (exposed), compared to individuals without such a condition (unexposed) - an analysis among all participants with a positive test result for COVID-19

From: COVID-19 related outcomes among individuals with neurodegenerative diseases: a cohort analysis in the UK biobank

 

No.(%) of cases

Odds Ratioa

Exposed

Unexposed

COVID-19 related death

 Any neurodegenerative disease

195/718 (27.2)

986/17220 (5.7)

2.08 (1.71, 2.53)

  Primary neurodegenerative diseases

132/512 (25.8)

1049/17426 (6.0)

1.91 (1.52, 2.40)

  Vascular neurodegenerative diseases

47/143 (32.9)

1134/17795 (6.4)

1.89 (1.29, 2.77)

  Other neurodegenerative diseases

98/322 (30.4)

1083/17616 (6.1)

2.16 (1.65, 2.82)

 Selected specific neurodegenerative diseases

  Alzheimer’s disease

54/220 (24.5)

1127/17718 (6.4)

1.58 (1.12, 2.21)

  Parkinson’s disease

52/196 (26.5)

1129/17742 (6.4)

1.97 (1.39, 2.78)

  1. a Odds Ratio (95%) were derived from logistic regression models, which were adjusted for birth year, sex, race/ethnicity, body mass index, smoking, alcohol use, Townsend deprivation index, annual household income, educational attainment, and Charlson Comorbidity Index