Table 2 Volumes of normalized subcortical brain structures with between-groups comparisons

Scaling factor for head size;

mean (95% CI)

1.38

(1.34–1.41)

1.47

(1.40–1.55)

1.51

(1.45–1.57)

0.005

< 0.0001

0.369

Range of scaling factor

1.15–1.62

1.26–1.69

1.32–1.69

Thalamus, ipsilesional;

median (IQR)^a

11,548

(10930–11,948)

9154

(5487–10,017)

9177

(8355–10,069)

< 0.0001

< 0.0001

0.617

Thalamus, contralesional;

mean (95% CI)

11,009

(10787–11,230)

10,312

(9872–10,752)

10,676

(10257–11,095)

0.003

0.128

0.171

Caudate nucleus, ipsilesional;

mean (95% CI)

5694

(5499–5889)

4905

(4083–5727)

4768

(4283–5252)

0.064

0.001

0.756

Caudate nucleus, contralesional;

mean (95% CI)

5861

(5684–6037)

5915

(5433–6397)

5770

(5416–6123)

0.787

0.638

0.537

Putamen, ipsilesional;

median (IQR)^a

7355

(6979–7911)

6332

(4198–7756)

7103

(5981–7496)

0.048

0.083

0.523

Putamen, contralesional;

mean (95% CI)

7326

(7130–7522)

7851

(7355–8348)

7217

(6889–7544)

0.050

0.545

0.027

Globus pallidus, ipsilesional;

median (IQR)^a

2443

(2331–2535)

2138

(1646–2346)

2231

(2099–2356)

< 0.001

< 0.001

0.277

Globus pallidus, contralesional;

mean (95% CI)

2501

(2443–2558)

2465

(2318–2612)

2540

(2397–2683)

0.633

0.600

0.444

Hippocampus, ipsilesional;

median (IQR)^a

5265

(4994–5451)

4422

(3875–5049)

4862

(4540–5283)

0.004

0.031

0.125

Hippocampus, contralesional;

mean (95% CI)

5293

(5141–5445)

5379

(5044–5714)

5210

(4933–5486)

0.586

0.583

0.361

Amygdala, ipsilesional,

mean (95% CI)

1610

(1504–1716)

1421

(1212–1629)

1537

(1377–1697)

0.068

0.458

0.334

Amygdala, contralesional;

mean (95% CI)

1540

(1454–1626)

1554

(1365–1743)

1562

(1416–1709)

0.877

0.796

0.936

Nucleus accumbens, ipsilesional;

mean (95% CI)

756

(711–801)

524

(416–633)

701

(601–802)

< 0.0001

0.268

0.004

Nucleus accumbens, contralesional;

median (IQR)^a

593

(534–692)

631

(477–705)

611

(523–686)

0.924

0.790

0.904