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Table 3 Logistic regression of the eGFR levels on in-hospital mortality and discharge disposition

From: Effects of estimated glomerular filtration rate on clinical outcomes in patients with intracerebral hemorrhage

 

Baseline eGFR (mL/min/1.73 m2)

 

≥90(n = 58,418)

60–89(N = 17,256)

45–59(N = 3507)

< 45(N = 5986)

P for trend

In-hospital mortality(N = 1975)

N = 955

N = 437

N = 157

N = 426

 

 Unadjusted model OR(95% CI)

Ref.

1.56 (1.39–1.75)

2.82 (2.37–3.35)

4.62 (4.1–5.19)

< 0.001

 Model 1 OR(95% CI)

Ref.

1.36 (1.21–1.53)

2.41 (2.02–2.88)

4.38 (3.89–4.93)

< 0.001

 Model 2 OR(95% CI)

Ref.

1.36 (1.21–1.53)

2.35 (1.97–2.82)

4.18 (3.7–4.72)

< 0.001

Non-routine discharge (N = 4952)

N = 3318

N = 979

N = 208

N = 447

 

 Unadjusted model OR(95% CI)

Ref.

1 (0.93–1.07)

1.11 (1.03–1.2)

2.15 (1.31–3.55)

< 0.001

 Model 1 OR(95% CI)

Ref.

1.05 (0.91–1.21)

1.19 (1.03–1.38)

4.17 (1.86–9.37)

< 0.001

 Model 2 OR(95% CI)

Ref.

1.11 (1.03–1.2)

1.16 (1–1.35)

1.37 (1.23–1.53)

< 0.001

Severe hemorrhagic stroke(N = 14,211)

N = 9373

N = 2909

N = 710

N = 1219

 

 Unadjusted model OR(95% CI)

Ref.

1.06 (1.01–1.12)

1.49 (1.36–1.64)

1.91 (1.77–2.07)

< 0.001

 Model 1 OR(95% CI)

Ref.

0.99 (0.94–1.04)

1.37 (1.24–1.51)

1.85 (1.71–2)

< 0.001

 Model 2 OR(95% CI)

Ref.

1 (0.95–1.05)

1.39 (1.26–1.53)

1.81 (1.67–1.96)

< 0.001

In-hospital complication

Pneumonia(N = 21,795)

N = 13,673

N = 4883

N = 1132

N = 2107

 

 Unadjusted model OR(95% CI)

Ref.

1.29 (1.24–1.34)

1.56 (1.45–1.68)

1.78 (1.68–1.88)

< 0.001

 Model 1 OR(95% CI)

Ref.

1.1 (1.06–1.15)

1.31 (1.21–1.41)

1.69 (1.59–1.78)

< 0.001

 Model 2 OR(95% CI)

Ref.

1.1 (1.05–1.14)

1.3 (1.2–1.4)

1.66 (1.57–1.76)

< 0.001

Hydrocephalus(N = 1862)

N = 1216

N = 352

N = 98

N = 196

 

 Unadjusted model OR(95% CI)

Ref.

0.98 (0.87–1.1)

1.35 (1.1–1.67)

1.59 (1.37–1.86)

< 0.001

 Model 1 OR(95% CI)

Ref.

0.99 (0.88–1.12)

1.37 (1.11–1.69)

1.6 (1.37–1.86)

< 0.001

 Model 2 OR(95% CI)

Ref.

0.99 (0.87–1.12)

1.37 (1.1–1.7)

1.54 (1.32–1.8)

0.0139

Recurrent intracerebral hemorrhage(N = 7026)

N = 4762

N = 1381

N = 316

N = 567

 

 Unadjusted model OR(95% CI)

Ref.

0.98 (0.92–1.04)

1.12 (0.99–1.26)

1.18 (1.08–1.29)

0.001

 Model 1 OR(95% CI)

Ref.

0.97 (0.91–1.03)

1.1 (0.98–1.24)

1.17 (1.07–1.29)

0.001

Model 2 OR(95% CI)

Ref.

0.96 (0.89–1.02)

1.02 (0.9–1.16)

1.07 (0.97–1.18)

0.489

Hematoma evacuation(N = 8901)

N = 6258

N = 1473

N = 326

N = 844

 

 Unadjusted model OR(95% CI)

Ref.

0.78 (0.73–0.83)

0.85 (0.76–0.96)

1.37 (1.27–1.48)

< 0.001

 Model 1 OR(95% CI)

Ref.

0.93 (0.88–0.99)

1.05 (0.93–1.18)

1.46 (1.35–1.58)

< 0.001

 Model 2 OR(95% CI)

Ref.

0.94 (0.88–1) 1.06 (0.94–1.2)

1.48 (1.37–1.61)

0.0247

  1. Model 1: Adjusted for age, sex
  2. Model 2: Adjusted for age, sex, BMI, current smoking, Prior stroke or TIA, Prior CHD or myocardial infarction, Hypertension, Dyslipidemia, Atrial fibrillation, Diabetes mellitus, PVD, Alcohol consumption
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BMC Neurology

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