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Table 2 Type of PD associated comorbidities

From: Criteria for identification of advanced Parkinson’s disease: the results of the Italian subgroup of OBSERVE-PD observational study

Symptoma

N (%)

APD

(N = 60)

Non-APD

(N = 80)

P between groups

(chi-square)

Depression

21 (35%)

13 (16.2%)

0.011

Cognitive dysfunction

33 (55%)

16 (20%)

 < 0.001

Sleep Disorders

12 (20%)

8 (10%)

0.096

Fatigue

15 (25%)

4 (5%)

0.001

Hypertension

18 (30%)

29 (36.2%)

NS

Cardiac abnormality

14 (23.3%)

22 (27.5%)

NS

Diabetes Mellitus

6 (10%)

2 (2.5%)

NS

Polyneuropathy/Neuropathy

4 (6.7%)

4 (5%)

NS

Chronic Kidney Disease or Insufficiency

2 (3.3%)

0

NS

Chronic Liver Disease or Insufficiency

1 (1.7%)

1 (1.2%)

NS

Chronic Pulmonary Disease

2 (3.3%)

1 (1.2%)

NS

Skin Disease

0

1 (1.2%)

NS

Orthostatism

3 (5%)

2 (2.5%)

NS

Chronic Gastrointestinal Disease

3 (5%)

4 (5%)

NS

Any malignancy

2 (3.3%)

1 (1.2%)

NS

Other

16 (26.7%)

17 (21.2%)

NS

No comorbidity

7 (11.7%)

20 (25%)

NS

  1. In bold the significant values are reported; aMultiple entries were possible