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Table 2 Type of PD associated comorbidities

From: Criteria for identification of advanced Parkinson’s disease: the results of the Italian subgroup of OBSERVE-PD observational study

Symptoma
N (%)
APD
(N = 60)
Non-APD
(N = 80)
P between groups
(chi-square)
Depression 21 (35%) 13 (16.2%) 0.011
Cognitive dysfunction 33 (55%) 16 (20%)  < 0.001
Sleep Disorders 12 (20%) 8 (10%) 0.096
Fatigue 15 (25%) 4 (5%) 0.001
Hypertension 18 (30%) 29 (36.2%) NS
Cardiac abnormality 14 (23.3%) 22 (27.5%) NS
Diabetes Mellitus 6 (10%) 2 (2.5%) NS
Polyneuropathy/Neuropathy 4 (6.7%) 4 (5%) NS
Chronic Kidney Disease or Insufficiency 2 (3.3%) 0 NS
Chronic Liver Disease or Insufficiency 1 (1.7%) 1 (1.2%) NS
Chronic Pulmonary Disease 2 (3.3%) 1 (1.2%) NS
Skin Disease 0 1 (1.2%) NS
Orthostatism 3 (5%) 2 (2.5%) NS
Chronic Gastrointestinal Disease 3 (5%) 4 (5%) NS
Any malignancy 2 (3.3%) 1 (1.2%) NS
Other 16 (26.7%) 17 (21.2%) NS
No comorbidity 7 (11.7%) 20 (25%) NS
  1. In bold the significant values are reported; aMultiple entries were possible