Table 2 Effects of high-dose and low-dose GCs on the treatment of AIDP
Parameters | High-dose(n=98) | Low-dose(n=91) | P value (two-tailed) |
|---|---|---|---|
Age (mean, years) | 48.49±17.94 | 51.85±17.37 | 0.286 |
Male, n (%) | 65(66.3) | 58 (63.7) | 0.761 |
Rural area, n (%) | 62(63.3) | 63(69.2) | 0.443 |
Hughes score on admission (mean, g) | 2.99±0.91 | 2.96±0.94 | 0.909 |
Hughes score at nadir (mean, g) | 3.28±0.88 | 3.74±0.74 | <0.001* |
Neurological symptoms, n (%) | |||
Facial/bulbar paralysis | 47(47.8) | 39(42.9) | 0.559 |
Oculomotor paralysis | 6(6.1) | 8(8.8) | 0.583 |
Paresthesia | 42(42.9) | 51(56.0) | 0.081 |
Hyperreflexia | 6(6.1) | 5(5.5) | 1.000 |
Complication, n (%) | |||
Autonomic dysfunction | |||
Hypertension | 17(17.3) | 21(23.1) | 0.413 |
Cardiac arrhythmia | 6(6.1) | 7(7.7) | 0.777 |
Urinary retention | 9(9.2) | 12(13.2) | 0.488 |
Deep venous thrombosis | 3(3.1) | 4(4.4) | 0.713 |
Dyspnoea | 28(28.6) | 21(23.1) | 0.411 |
Pulmonary infection | 9(9.2) | 19(20.9) | 0.026* |
Diabetes | 9(9.2) | 7(7.7) | 0.797 |
Laboratory abnormality, n (%) | |||
Hyponatraemia | 22(22.4) | 31(34.1) | 0.105 |
Hypoalbuminaemia | 19(19.4) | 23(25.3) | 0.383 |
Hospital stay (days) | 13.27±8.47 | 15.16±7.62 | 0.023* |
Mechanical ventilation, n (%) | 11(11.2) | 8(8.8) | 0.635 |
Death in hospital stay, n (%) | 1(1.0) | 0 | - |
Hughes score at discharge (g) | 2.36±1.03 | 2.68±0.88 | 0.005* |
Hughes score of 3 months after onset (g) | 1.83±1.30 | 2.30±0.89 | <0.001* |