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Table 1 Biochemical and serological results

From: Acute disseminated encephalomyelitis with bilateral optic neuritis following ChAdOx1 COVID-19 vaccination

Biochemistry and serology results

Result

Normal Range

Platelet count

225 × 109/L

150- 400 × 109/L

Vitamin D

60 nmol/L

50 -140 nmol/L

Folate

29.1 nmol/L

7 – 46.4 nmol/L

Vitamin B12

309 pmol/L

138- 652 pmol/L

Beta 2 glycoprotein antibodies

6 U/ml

 < 20 U/ml

Cardiolipin IgG

 < 3 U/ml

 < 20 U/ml

Cardiolipin 1gM

2 U/ml

 < 20 U/ml

Anti nuclear antibodies

Not detected

 

Extractable nuclear antibodies

Not detected

 

Anti-neutrophil cytoplasmic antibodies

Not detected

 

Serum aquaporin 4 antibodies

Negative

 

CSF aquaporin 4 antibodies

Negative

 

Serum myelin oligodendrocyte glycoprotein antibody

Negative

 

CSF PCR testing—N meningitidis DNA, S pneumoniae DNA, Herpes simplex virus type 1 DNA, Herpes simplex virus type 2 DNA, Human parechovirus RNA, VZV DNA, Enterovirus RNA

Not detected

 

CSF Glucose

4.8 mmol/L

2.8 – 4.5 mmol/L

CSF Protein

0.4 g/L

0.19 – 0.56 g/L

CSF White cells

59 × 106/L (99% mononuclear)

 < 5 × 106/L

CSF Red cells

3 × 106/L

 < 1 × 106/L

CSF culture

Negative

 

CSF IgG

0.06 g/L

 < 0.03 g/L

Serum IgG

12.4 g/L

7- 16 g/L