Date | 2020/04 | 2020/07 | 2020/11 |
---|---|---|---|
Clinical syndrome | Bilateral calf and thigh muscle cramping and twitching. | Bilateral calf and thigh muscle cramping improved. | Bilateral calf and thigh muscle twitching recurred. |
LGI1a antibody titer | 1:10 | Negative | 1:10 |
CASPR2b antibody titer | 1:100 | Negative | Negative |
Chest computed tomography | Malignant thymoma (8.7 cm) with pleural and great vessel involvement. | Malignant thymoma with regression (4.5 cm). | Malignant thymoma with suspicion of post-radiation changes or progression (5.7 cm). |
High-rate (50%) repetitive nerve stimulation test | Incremental response (102%) | Normal | Nil |