Fig. 4From: Adjunctive treatment of chronic migraine using an oral dental device: overview and results of a randomized placebo-controlled crossover studyImproper NTI Protocol. Arrows indicate canine contact on the NTI device when the patient’s jaw shifts laterally. Canine contact allows for intense trigeminal motor hyperactivity (clenching), creating considerable strain to the contralateral temporomandibular joint, potentially producing excessive nociceptionBack to article page