Skip to main content

Table 2 Comparison between autism spectrum disorder (ASD) and typically developing (TD) children of the urinary metabolites using standardized canonical discriminant function

From: Urinary metabolomics using gas chromatography-mass spectrometry: potential biomarkers for autism spectrum disorder

Urine organic acids in pseudo units

ASD

TD

Test of Equality of Group Means

Discriminant Function Coefficients

Mean

(SD)

Mean

(SD)

Wilk’s Lambda

F

Sig.

 

3-hydroxy isovaleric

0.20(0.14)

1.05(1.12)

0.697

36.035

< 0.0001

−0.812

Indoleacetic acid

0.61 (0.91)

0.02 (0.04)

0.908

8.455

0.005

−0.342

Adipic acid

1.54(2.38)

0.01 (0.04)

0.911

8.095

0.006

0.277

Suberic acid

1.28(2.35)

0.005 (0.022)

0.934

5.849

0.018

0.148

Homovanillic acid

10.07(6.8)

6.60(2.41)

0.941

5.178

0.025

0.404

3-hydroxy butyric acid

0.57(0.72)

0.25 (0.17)

0.955

3.889

0.052

0.107

Lactic acid

1.71 (1.37)

0.79 (3.46)

0.964

3.137

0.080

0.568

Citric acid

34.80(39.1)

17.58 (46.12)

0.968

2.725

0.103

0.052

2-ketoglutaric acid

5.98(12.04)

3.62(11.64)

0.993

0.598

0.442

−0.146

4-hydroxyphenyl acetic acid

32.40 (56.4)

23.57(33.2)

0.995

0.441

0.509

−0.015