Table 2 Comparation within-groups and differences group-by-time interaction for primary outcomes
Baseline Final assessment | Baseline Follow-up 1 | Baseline Follow-up 2 | Baseline Follow-up 3 | Interaction group*time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean change (95%CI) | p value | Mean change (95%CI) | p value | Mean change (95%CI) | p value | Mean change (95%CI) | p value | F; df; p value | ||
Primary outcomes | Groups | |||||||||
Frequency of headachea | IG SUG | 1.13 (-2.29; 4.57) 1.16 (-2.06; 4.38) | 0.513 0.477 | 1.19 (-2.23; 4.62) 1.01 (-2.21; 4.23) | 0.492 0.536 | 2.07 (-1.35; 5.51) 0.41 (-2.81; 3.63) | 0.233 0.801 | 2.43 (-1.00; 5.86) 0.01 (-3.21; 3.23) | 0.163 0.994 | 0.44; 4; 0.782 |
Intensity of pain (NRS) | IG SUG | 2.96 (2.03; 3.90) 3.73 (2.85; 4.62) | 0.001*CR 0.001*CR | 3.31 (2.38;4.25) 2.78 (1.90; 3.67) | 0.001*CR 0.001*CR | 3.96 (3.03; 4.90) 3.53 (2.65; 4.42) | 0.001*CR 0.001*CR | 4.02 (3.08;4.96) 3.38 (2.50; 4.27) | 0.001*CR 0.001*CR | 1.51; 4; 0.202 |