Subthalamic nucleus-deep brain stimulation improves autonomic dysfunctions in Parkinson’s disease

BMC Neurology

Table 1 Comparison of preoperative and postoperative clinical state [M (IQR)]

Time	Preoperative	Postoperative			Total P	χ2	P₁	P₂	P₃
Time	Preoperative	1 month	3 month	6 month	Total P	χ2	P₁	P₂	P₃
SCOPA-Aut
SCOPA-Aut (0–69) total	22 (12)	18 (14)	18 (10)	16 (12)	0.003	5.399	0.001	0.001	< 0.001
Gastrointestinal (Q1–7)	4 (2.8)	4 (4)	4 (2.8)	4 (2)	0.107	2.133	0.062	0.193	0.065
Urinary (Q8–13)	7 (4)	4.5 (3.8)	4 (5)	4 (5)	< 0.001	11.062	< 0.001	< 0.001	< 0.001
Cardiovascular (Q14–16)	2 (1.8)	2 (1)	2 (1.7)	2 (2)	0.248	1.418	0.049	0.107	0.345
Thermoregulatory (Q17–21)	4 (2)	3 (2.8)	3 (3)	3 (2.8)	< 0.001	8.049	< 0.001	< 0.001	< 0.001
Pupillomotor (Q19)	1 (2)	1 (2)	1 (2)	1 (2)	0.264	1.362	0.159	0.073	0.088
Sexual (Q22–25)	2 (1.7)	2 (2)	2 (1)	2 (1.7)	0.792	0.346	0.659	0.871	0.542
HAMA (0–56)	16 (14)	11 (11)	9 (10)	11 (11)	< 0.001	12.839	< 0.001	< 0.001	< 0.001
HAMD (0–68)	14 (13)	9 (9)	9 (8)	9 (9)	< 0.001	11.664	0.004	< 0.001	< 0.001

P₁, P₂ and P₃ values are, respectively, the results of comparisons between preoperative results and results 1, 3 and 6 months after surgery, SCOPA-Aut the Scale for Outcomes in PD for Autonomic Symptoms, HAMA Hamilton Anxiety Rating Scale, HAMD Hamilton Depression Rating Scale

ISSN: 1471-2377