Table 1 Baseline characteristics, clinical symptoms and laboratory and MRI findings of patients with ICH before and during the COVID-19 pandemic

Mean age, y

67.0 ± 13.9

68.3 ± 13.5

57.8 ± 14.3

0.027

Male gender, n (%)

67 (65)

58 (64)

9 (75)

0.655

BMI, kg/m², a

23.0 ± 4.1

23.0 ± 4.0

23.0 ± 5.2

0.85

Systolic BP, mmHg

172.3 ± 52.7

171.5 ± 54.7

178.3 ± 34.6

0.441

Diastolic BP, mmHg

95.0 ± 22.4

93.7 ± 22.1

104.8 ± 24.6

0.057

 Hypertension

93 (90)

84 (92)

9 (75)

0.166

 Diabetes mellitus

20 (19)

19 (21)

1 (8)

0.519

 Dyslipidemia

64 (62)

60 (66)

4 (33)

0.061

 Smoking

24 (23)

20 (22)

4 (33)

0.609

 Chronic kidney disease

20 (19)

19 (21)

1 (8)

0.519

 Atrial fibrillation

11 (11)

10 (11)

1 (8)

0.828

 Ischemic heart disease

11 (11)

10 (11)

1 (8)

0.828

 History of stroke

17 (17)

16 (18)

1 (8)

0.691

 Oral anticoagulants

11 (11)

10 (11)

1 (8)

0.828

 Antiplatelet agents

19 (18)

18 (20)

1 (8)

0.572

 mRS before ICH

0.5 ± 1.1

0.6 ± 1.1

0.2 ± 0.6

0.189

 NIHSS on admission

8.5 ± 9.1

8.4 ± 9.4

9.4 ± 6.4

0.285

 mRS at discharge

2.5 ± 1.9

2.4 ± 1.9

2.7 ± 1.8

0.646

 NIHSS at discharge

6.6 ± 11.6

6.6 ± 11.8

6.6 ± 10.3

0.386

 Neurological deterioration with NIHSS ≥4

7 (7)

6 (7)

1 (8)

0.7

 Death during hospitalization

6 (6)

6 (7)

0 (0)

0.794

Latency from ICH onset to radiological imaging, b

269 ± 314

290 ± 334

149 ± 113

0.106

 Hematoma volume (cm³)

16.8 ± 26.5

17.1 ± 27.9

14.6 ± 11.1

0.371

 Hematoma expansion

7 (7)

10 (11)

2 (17)

0.922

 Intraventricular penetration

34 (33)

31 (34)

3 (25)

0.763

 Location of hemorrhage

0.245

  Thalamus

28 (27)

26 (29)

2 (17)

  Putamen

38 (37)

30 (33)

8 (67)

  Subcortical

26 (25)

25 (27)

1 (8)

  Infratentorium

7 (7)

6 (7)

1 (8)

  Others

4 (4)

4 (4)

0 (0)

 PVH

1.3 ± 0.9

1.3 ± 0.9

1.3 ± 0.9

0.69

 DSWMH

1.1 ± 0.9

1.1 ± 0.9

0.8 ± 0.6

0.208

 CMBs

67 (68)

59 (69)

8 (67)

0.844

Latency from ICH onset to blood sampling, b

244 ± 310

266 ± 330

123 ± 100

0.239

 LDL-C, mg/dl, a

111.1 ± 41.6

111.8 ± 42.9

106.3 ± 28.9

0.783

 HDL-C, mg/dl, a

56.2 ± 19.5

56.2 ± 20.0

56.6 ± 14.7

0.835

 Triglyceride, mg/dl, a

127.0 ± 99.6

123.9 ± 95.7

150.3 ± 126.8

0.763

 eGFR (ml/min)

78.0 ± 31.1

76.8 ± 31.3

86.8 ± 29.4

0.149

 BS (mg/dl)

129.9 ± 39.3

131.9 ± 41.3

114.4 ± 14.6

0.113

 Hemoglobin A1c (%), c

5.8 ± 0.7

5.8 ± 0.7

5.7 ± 0.3

0.717

 Hs-CRP (mg/dl)

0.4 ± 1.2

0.4 ± 1.3

0.2 ± 0.3

0.491

 PT-INR, a

1.12 ± 0.40

1.13 ± 0.40

1.09 ± 0.43

0.025

 APTT/Control, a

1.02 ± 0.19

1.02 ± 0.19

1.07 ± 0.19

0.253

 D-dimer (μg/ml), a

4.2 ± 15.7

4.5 ± 16.6

1.4 ± 1.0

0.44