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Table 1 Demographics and Clinical Characteristics of the patients in the development and validation cohorts

From: Nomogram to predict hemorrhagic transformation for acute ischemic stroke in Western China: a retrospective analysis

  development cohort (n = 392) validation cohort (n = 178)
Demographics
 Age, y, median (IQR) 70(60–79) 72(61–81)
 Age > 60 y, n (%) 287(73.2) 136(76.4)
 Male sex, n (%) 236(60.2) 102(57.3)
Medical history, n (%)
 Hypertension 288(73.5) 131(73.6)
 Diabetes mellitus 125(31.9) 62(34.8)
 Previous stroke 53(13.5) 50(28.1)
 Atrial fibrillation 80(20.9) 36(20.2)
 Antiplatelet 53(13.5) 48(27.0)
 Oral anticoagulant 13(3.3) 21(11.8)
 Smoking current 147(37.5) 62(34.8)
Baseline data, median (IQR)
 Systolic BP, mm Hg, 153(137–171) 157(138–175)
 Diastolic BP, mm Hg, 88(80–99) 88(77–99)
 Temperature,°C 36.5(36.4–36.7) 36.5(36.2–36.7)
 Glucose, mmol/L 6.32(5.15–8.31) 7.47(6.15–9.59)
 Total cholesterol (TC), mmol/L 4.78(4.06–5.45) 4.81(4.08–5.58)
 Triglyceride (TG), mmol/L 1.33(1.01–1.88) 1.51(1.06–2.33)
 High-density lipoprotein (HDL), mmol/L 1.06(0.91–1.25) 1.39(1.14–1.65)
 Low-density lipoprotein (LDL), mmol/L 2.90(2.20–3.51) 2.76(2.17–3.31)
 Blood platelet (PLT), × 109/L 179.00(135.25–215.75) 194.00(154.75–226.50)
 Prothrombin time (PT)% 99.00(90.00–109.00) 91.64(81.34–101.97)
 APTT, s 35.20(32.40–37.88) 28.40(26.00–30.53)
 INR 1.00(0.95–1.07) 1.04(0.99–1.10)
 Fibrous Protein (Fib), g/L 3.29(2.84–3.94) 3.04(2.57–3.52)
Imaging data, median (IQR)
 Cerebral Infarction Area (CIA), cm2 3.00(1.00–9.69) 3.16(0.99–19.09)
 Cerebral Infarction Volume (CIV), cm3 3.87(0.78–19.31) 3.78(0.72–43.28)
Scores
 THRIVE score, median (IQR) 2.00(2.00–3.75) 3.00(2.00–4.00)
 NIHSS score, median (IQR) 5(3–9) 6 (4–16)
 NIHSS score > 20, n (%) 11(2.8) 22(12.7)
Treament
 onset-to-treatment (OTT), h, median (IQR) 13.50(5.00–48.00) 7.00(2.00–24.00)
 Thrombolysis or ET, n (%) 21(5.4) 32(18.5)
  1. APTT activated partial thromboplastin time, INR international normalized ratio, NIHSS National Institutes for Health Stroke Scale