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Table 2 Univariate analysis of the variables associated with HT in the development cohort

From: Nomogram to predict hemorrhagic transformation for acute ischemic stroke in Western China: a retrospective analysis

  HT (n = 48) Non-HT (n = 344) P Value
Demographics
 Age, y, median (IQR) 71.50(62.00–77.00) 70.00(59.25–79.00) 0.672
 Age > 60 y, n (%) 39(81.3) 248(72.1) 0.180
 Male sex, n (%) 29(60.4) 207(60.2) 0.974
Medical history, n (%)
 Hypertension 32(66.7) 256(74.4) 0.254
 Diabetes mellitus 18(37.5) 107(31.1) 0.373
 Previous stroke 7(14.6) 46(13.4) 0.818
 Atrial fibrillation 28(58.3) 52(15.1) 0.000*
 Antiplatelet 4(8.3) 49(14.2) 0.262
 Oral anticoagulant 3(6.3) 10(2.9) 0.435
 Smoking current 14(29.2) 133(38.7) 0.203
Baseline data, median (IQR)
 Systolic BP, mm Hg, 140.00(130.00–167.00) 154.50(139.25–172.00) 0.024*
 Diastolic BP, mm Hg, 81.00(75.25–92.00) 80.00(80.00–100.00) 0.053*
 Temperature,°C 36.55(36.40–36.90) 36.50(36.40–36.68) 0.045*
 Glucose, mmol/L 6.61(5.93–11.43) 6.23(5.07–7.91) 0.015*
 TC, mmol/L 4.22(3.81–5.09) 4.83(4.11–5.47) 0.004*
 TG, mmol/L 1.28(0.94–1.69) 1.36(1.01–1.90) 0.212
 HDL, mmol/L 1.04(0.85–1.27) 1.06(0.91–1.25) 0.411
 LDL, mmol/L 2.72 ± 0.90 2.91 ± 0.95 0.200
 PLT, ×109/L 158.50(127.50–211.25) 180.00(141.00–216.00) 0.169
 PT% 93.50(84.25–104.50) 100.50(92.00–110.00) 0.002*
 APTT, s 35.60(32.43–38.45) 35.20(32.40–37.80) 0.359
 INR 1.04(0.97–1.11) 1.00(0.95–1.06) 0.009*
 Fib, g/L 3.59(3.08–4.66) 3.27(2.82–3.87) 0.003*
Imaging data, median (IQR)
 Cerebral Infarction
Area (CIA), cm2
16.43(8.81–29.52) 2.22(0.92–7.10) 0.000*
 Cerebral Infarction
Volume (CIV), cm3
32.58(15.4179.20) 2.51(0.62–12.81) 0.000*
Scores
 THRIVE score, median (IQR) 4.00(3.00–5.75) 2.00(2.00–3.00) 0.000*
 NIHSS score, median (IQR) 11.50(6.25–15.00) 4.00(3.00–8.00) 0.000*
 NIHSS score > 20, n (%) 7(14.6) 4(1.2) 0.000*
Treament
 OTT, h, median (IQR) 15.00(3.00–48.00) 13.50(5.00–48.00) 0.757
 Thrombolysis or ET, n (%) 6(12.5) 15(4.4) 0.019*
  1. TC total cholesterol, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein, PLT blood platelet, PT Prothrombin time, APTT activated partial thromboplastin time, INR international normalized ratio, Fib fibrous protein, NIHSS National Institutes for Health Stroke Scale, OTT onset-to-treatment, * p<0.1