Table 2 NSAA score (Mean ± SD) in mutation type groups (deletion, duplication, nonsense and splice site) at each time point

3

11.97 ± 3.23

12.6 ± 3.6

14.11 ± 2.35

9.5 ± 3.54

n = 120

n = 10

n = 19

n = 2

3.5

18.99 ± 4.95

20 ± 5.7

22.26 ± 4.16

16.5 ± 6.36

n = 120

n = 10

n = 19

n = 2

4

23.04 ± 6.43

25 ± 7.04

26.63 ± 6.37

18.5 ± 6.36

n = 118

n = 10

n = 19

n = 2

5

22.08 ± 6.4

24.4 ± 6.88

25.74 ± 6.44

18.5 ± 6.36

n = 114

n = 10

n = 19

n = 2

6

20.55 ± 6.27

23.4 ± 6.79

24.05 ± 7.34

18.5 ± 6.36

n = 106

n = 10

n = 19

n = 2

7

18.87 ± 6.71

21.22 ± 6.89

21.05 ± 7.31

16 ± 5.66

n = 100

n = 9

n = 19

n = 2

8

17 ± 7.05

19.86 ± 6.77

18.5 ± 6.82

16 ± 5.66

n = 95

n = 7

n = 18

n = 2

9

14.54 ± 7.02

18.57 ± 5.8

16.71 ± 7.22

15 ± 7.07

n = 81

n = 7

n = 17

n = 2

10

13.06 ± 7.36

15.8 ± 7.09

14.13 ± 8.13

13.5 ± 7.78

n = 70

n = 5

n = 16

n = 2

11

11.43 ± 7.36

15 ± 7.55

13.2 ± 8.78

6

n = 63

n = 5

n = 15

n = 1

12

9.71 ± 7.7

13.25 ± 10.37

12 ± 9.91

4

n = 57

n = 4

n = 14

n = 1