Fig. 6

Blocking the LPA receptors can reduce the expression of μ-calpain and AT8. Western blotting measured μ-calpain in neurons pretreated with LPA1 and LPA2 receptor inhibitors (a,b). Immunofluorescence analysis of AT8 in neurons with the same treatment (c). Data are presented as the mean ± S.E.M. from three independent cell experiments, **P < 0.01