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Table 1 Clinical profiles of the patients who completed follow-up

From: Memantine for the patients with mild cognitive impairment in Parkinson’s disease: a pharmacological fMRI study

 

Age (years)

Duration (years)

UPDRS part3

L-DOPA (mg)

LEDD (mg)

Patient 1

68

9

31

350

0

Patient 2

72

3

20

250

0

Patient 3

69

2

8

100

100

Patient 4

66

2

19

200

0

Patient 5

72

2

18

200

0

Patient 6

66

4

19

300

75

Patient 7

69

7

17

400

75

Patient 8

74

8

8

150

50

Patient 9

68

9

17

200

150

Patient 10

67

5

13

0

135

Mean ± SD

69.0 ± 2.7

5.1 ± 2.9

17.0 ± 6.6

215.0 ± 118.0

58.5 ± 58.0

 

MMSE

MoCA

PASAT

TMT-A (sec)

TMT-B (sec)

Patient 1

25

20

21

79

420

Patient 2

29

24

28

69.7

238

Patient 3

27

25

28

39.5

159

Patient 4

28

21

19

48.4

151.4

Patient 5

29

23

32

77.4

194.4

Patient 6

26

17

18

100.6

379.8

Patient 7

25

18

18

65.4

420

Patient 8

26

19

16

53.6

107

Patient 9

25

18

8

56.8

167.3

Patient 10

25

16

26

104.7

357

Mean ± SD

26.5 ± 1.6

20.1 ± 3.1

21.4 ± 7.1

69.5 ± 21.4

259.4 ± 121.9

  1. Duration Disease duration, UPDRS part3 motor sections of United Parkinson’s Disease Rating Scale, L-DOPA dosage of L-DOPA, LEDD L-dopa equivalent daily dose of dopamine agonist, MoCA Montreal Cognitive Assessment, PASAT Paced Auditory Serial Addition Test, TMT-A time to complete part A of the Trail Making Test, TMT-B time to complete part B of the Trail Making Test, sec seconds