Training set RNA-seq cohort (n = 661) | |||
 | Low-risk score | High- risk score |  |
Features | n = 333 | n = 332 | P- value |
Age | |||
  ≤ 65 | 316 | 259 | < 0.0001 |
 >65 | 16 | 70 |  |
Gender | |||
 Male | 180 | 202 | ns |
 Female | 152 | 127 |  |
Grader | |||
 LGG | 328 | 175 | < 0.0001 |
 GBM | 4 | 154 |  |
Vital status | |||
 Alive | 48 | 171 | < 0.0001 |
 Dead | 284 | 158 |  |
Testing set RNA-seq cohort(n = 465) | |||
 | Low-risk score | High- risk score |  |
Features | n = 165 | n = 115 | P- value |
Age | |||
  ≤ 65 | 189 | 255 | < 0.05 |
 >65 | 3 | 18 |  |
Gender | |||
 Male | 102 | 164 | ns |
 Female | 90 | 109 |  |
Grader | |||
 LGG | 164 | 135 | < 0.0001 |
 GBM | 28 | 138 |  |
Vital status | |||
 Alive | 125 | 76 | < 0.0001 |
 Dead | 67 | 197 |  |