Table 3 The comparison SUVR, cerebrospinal fluid NEAT1, miR-27a-3p, BACE1, Aβ 42 and Aβ 40 level in AD patients and control group (−x ± s)
Group | Cases | NEAT1/GAPDH | miR-27a-3p/U6 | BACE1(ng/mL) | Aβ 40(pg/mL) | Aβ 42(pg/mL) | SUVR | Aβ 42/ Aβ 40 |
|---|---|---|---|---|---|---|---|---|
Control group | 32 | 1.01 ± 0.23 | 1.03 ± 0.31 | 21.39 ± 3.73 | 10,708.99 ± 1979.17 | 499.99 ± 53.63 | 0.74 ± 0.15 | 0.048 ± 0.010 |
Mild group | 41 | 3.51 ± 1.24# | 0.48 ± 0.10# | 55.78 ± 5.98# | 10,477.95 ± 2192.92# | 303.55 ± 36.77# | 1.50 ± 0.29# | 0.030 ± 0.008# |
Moderate to severe group | 25 | 4.30 ± 1.65#* | 0.35 ± 0.10#* | 72.32 ± 16.08#* | 11,019.63 ± 2807.62#* | 231.45 ± 34.14#* | 1.76 ± 0.52#* | 0.022 ± 0.007#* |
F value | – | 65.263 | 102.897 | 234.697 | 0.432 | 321.684 | 75.791 | 73.370 |
P value | – | 0.000 | 0.000 | 0.000 | 0.651 | 0.000 | 0.000 | 0.000 |