Table 1 Clinical and demographic characteristics of the whole cohort at baseline visit
Patient No./ Age(y)/Gender | Admission time since onset of symptoms | Subgroups of acute AOP infarction | Risk factors | Aetiologies | Symptoms | MRS after 90 days | Treatment |
|---|---|---|---|---|---|---|---|
1/65/F | 1 hour | Paramedian bithalami | Cho, DM, HTN | Arteriosclerosis of right PCA | Hypersomnia; Vertical gaze palsy. | 2 | Aspirin 200 mg/d orally |
2/71/F | 2 hours | Paramedian bithalami rostral midbrain | Smoke, DM, HTN, CAD | Small vessel disease | Coma; Vertical gaze palsy; Oculomotor nerve palsy; Movement disorders. | 3 | Aspirin 200 mg/d orally |
3/68/M | 3 hours | Paramedian bithalami | Smoke, Cho, DM, HTN, CAD | Arteriosclerosis of BA | Hypersomnia; Movement disorders; Aphasia; Hypomnesis. | 2 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
4/66/M | 1 hours | Paramedian bithalami | DM, HTN, CAD | Arteriosclerosis of left PCA | Coma; Movement disorders. | 0 | Alteplase |
5/63/M | 2 hours | Paramedian bithalami anterolateral thalami | Smoke, Drinking, HTN | Sinus bradycardia | Hypersomnia; Hypomnesis; Disorientation; Movement disorders; Corticospinal tract signs. | 2 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
6/69/M | 5.5 hours | Paramedian bithalami rostral midbrain | Cho, DM, HTN, CAD | Arteriosclerosis of left PCA | Hypersomnia; Oculomotor nerve palsy; Movement disorders. | 4 | Aspirin 200 mg/d orally |
7/45/M | 8 hours | Paramedian bithalami red nucleus | Cho, DM, HTN | Atrial fibrillation | Hypersomnia; Barylalia; Ataxia; Dysarthria. | 3 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
8/64/M | 1 hours | Paramedian bithalami | Smoking, Cho, DM, HTN | Small vessel disease | Hypersomnia; Barylalia; Movement disorders. | 1 | Alteplase |
9/60/M | 2.5 hours | Paramedian bithalami rostral midbrain | Cho, DM, HTN | Atrial fibrillation | Hypersomnia; Disorientation; Hypomnesis; Movement disorders. | 3 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
10/67/M | 10.5 hours | Paramedian bithalami rostral midbrain | Smoke, Cho, DM, HTN | Small vessel disease | Coma; Vertical gaze palsy; Hypomnesis; Disorientation; Oculomotor nerve palsy; Movement disorders. | 4 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
11/29/F | 4.5 hours | Paramedian bithalami anterolateral thalami | Smoke | Small vessel disease | Coma; Hypomnesis; Disorientation. | 1 | Alteplase |
12/43/F | 2.5 hours | Paramedian bithalami | Cho, DM, HTN | Endocarditis | Coma; Hemiplegia. | 1 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
13/77/M | 6 hours | Paramedian bithalami rostral midbrain | Smoking, DM, HTN | Atrial fibrillation | Coma; Vertical gaze palsy; Disorientation; Oculomotor nerve palsy; Movement disorders. | 4 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
14/55/F | 5.5 hours | Paramedian bithalami | Cho, DM, HTN | Small vessel disease | Cerebellar ataxia; Barylalia. | 2 | Alteplase |
15/60/M | 1 hour | Paramedian bithalami | Smoking, Cho, HTN | Small vessel disease | Drowsiness; Vertical gaze palsy. | 2 | Aspirin 200 mg/d orally |
16/67/M | 6 hours | Paramedian bithalami | Cho, DM, HTN | Small vessel disease | Hypersomnia; Barylalia. | 2 | Alteplase |
17/53/M | 1.5 hours | Paramedian bithalami | Smoke | Atrial myxoma | Drowsiness; Movement disorders. | 1 | Low-molecular-weight heparins calcium injection (4000 IU/12 h) |
18/64/F | 2 hours | Paramedian bithalami rostral midbrain | Cho, DM, HTN | Arteriosclerosis of right PCA | Drowsiness; Cerebellar ataxia; Vertical gaze palsy; Oculomotor nerve palsy; Movement disorders. | 4 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
19/66/M | 2.5 hours | Paramedian bithalami anterolateral thalami | Cho, DM | Small vessel disease | Hypersomnia; Hypomnesis; Vertical gaze palsy. | 1 | Alteplase |
20/75/F | 3 hours | Paramedian bithalami rostral midbrain | Cho, DM, HTN | Atrial myxoma | Drowsiness; Cerebellar ataxia; Vertical gaze palsy; Oculomotor nerve palsy; Movement disorders. | 5 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
21/23/M | 4 hours | Paramedian bithalami | Smoke | Basilar artery dissection | Drowsiness. | 2 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
22/30/F | 3 hours | Paramedian bithalami | – | Basilar artery dissection | Coma; Aphasia; Movement disorders. | 2 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |
23/65/M | 1 hour | Paramedian bithalami | Smoking, Drinking,Cho,DM | Small vessel disease | Hypersomnia; Hypomnesis; Hemiplegia. | 1 | Aspirin 200 mg/d combined with clopidogrel 7.5 mg/d |