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Table 2 Clinical, neuroimaging features and outcome of patients with neurological symptoms after vaccinating inactivated COVID-19 vaccine

From: Inactivated COVID-19 vaccine induced acute stroke-like focal neurologic symptoms: a case series

Characteristics n = 19
Neurological symptoms, n (%)
 Unilateral numbness 18 (94.7)
 Headache at the initial presentation 10 (52.6)
 Headache during the course 17 (89.5)
 Unilateral weakness 9 (47.4)
 Nausea /vomiting 4 (21.1)
 Perioral numbness 3 (15.8)
Neurological deficits, n (%)
 Sensory deficits 15 (79)
 Motor deficits 10 (52.6)
 Tongue deviation 5 (26.3)
Time of neurological symptom after vaccination, mins (median, IQR) 55 (21,661)
Time to complete recovery
  < 24 h 0 (0)
 24–72 h 1 (5.3)
 72 h -1 week 3 (15.8)
 1–2 weeks 8 (42.1)
 2–4 weeks 2 (10.5)
  > 4 weeks 5 (26.3)
Brain imaging
 Initial CT brain with normal findings, n (%) 15 (78)
 Time from symptom onset to CT scan, hr, median (IQR) 6.04 (2.3,13.5)
 Initial MRI brain with normal findings, n (%), n (%) 19 (100)
 Time from symptom onset to MRI scan, hr, median (IQR) 2.56 (1.6, 7.5)
 Non-invasive vascular imaging (CTA/MRA), n (%) 19 (100)
  No vascular abnormality 16 (84.2)
  Dynamic angiographic change in luminal narrowing, n (%) 3 (15.8)
Outcomes
 NIHSS
  Initial, median (IQR) 1 (1,2.5)
  at 2-week, median (IQR) 0 (0,0)
  at 4-week, median (IQR) 0 (0,0.5)
 mRS
  Initial, median (IQR) 1 (0.5,2)
  at 2-week, median (IQR) 0 (0,1)
  at 4-week, median (IQR) 0 (0,1)
  1. Abbreviation: CT computed tomography, IQR inter quartile range, MRI magnetic resonance imaging, mRS modified rankin scale, NIHSS national institute of health stroke scale