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Table 2 Trend of the headache days after increase in the onabotulinumtoxinA dose. (n = 175)

From: OnabotulinumtoxinA in chronic migraine: is the response dose dependent?

 

Number of the headache days

Number of the severe headache days

Baseline

25.85 ± 5.73

15.20 ± 7.96

36 weeks before the increase

14.22 ± 10.81

5.88 ± 6.80

24 weeks before the increase

13.58 ± 10.91

5.46 ± 6.75

12 weeks before the increase

13.71 ± 10.62

5.32 ± 6.49

Day of the increase to 200 units

13.62 ± 10.79

5.88 ± 6.73

12 weeks after the increase

11.88 ± 10.55 *

4.33 ± 5.23 **

24 weeks after the increase

12.38 ± 10.69

3.83 ± 4.96 **

36 weeks after the increase

11.02 ± 10.61 **

4.01 ± 4.89 **

  1. Data presented as mean ± SD; * P < 0.01, ** P < 0.001 for the paired t-test compared to the day of increase to 200 units