Homocysteine is related to enlarged perivascular spaces in the brainstem in patients with isolated pontine infarction

Table 5 Multivariable linear regression full model for tHcy ^{c, d}

variable	B	standardized β	95%CI	P value
Sex, male	-0.138	-0.134	-0.295-0.019	0.085
Age	-0.001	-0.015	-0.009-0.008	0.855
SBP	0.002	0.074	-0.002-0.006	0.329
DBP	-0.001	-0.026	-0.008-0.006	0.733
FPG	-0.038	-0.217	-0.077-0.000332	0.052
HbA1c	0.014	0.061	-0.036--0.064	0.585
Current smoking	0.179	0.170	0.025-0.333	0.023*
CCrE	-0.002	-0.103	-0.006-0.001	0.183
Uric acid	0.00042	0.076	-0.000291-0.001	0.245
BG-EPVS grade	0.110	0.162	0.024-0.197	0.013*
brainstem-EPVS	0.273	0.264	0.143-0.402	<0.001*

Abbreviations: tHcy total homocysteine, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HbA1c glycosylated hemoglobin, CCrE estimated creatinine clearance, EPVS enlarged perivascular spaces, BG the basal ganglia, CI confidence interval
^c tHcy levels were transformed to a natural logarithmic scale
^d Age, sex, and other factors with P < 0.05 in simple linear regression analyses were included in the multivariate model
* P < 0.05

ISSN: 1471-2377