Table 2 Sweat gland tumors with intracranial invasion

Bradbury [15]

1984

79

Male

External auditory meatus

3 × 4

-

Intracerebral

-

13 years

Hidradenoma

Res (intradural)

-

-

1 year

Local

Alive

Urbanski [24]

1985

68

Female

Parietal

grapefruit-size

-

Epidural; intracerebral

-; TS

many years

Cylindroma

Res with scalp, skull

2nd Res with skull and dura;

3rd Res

 < 1 year; < 24 months

3 years

Local

Alive

Sridhar [26]

1989

60

Female

NA

NA

NA

Skull; epidural and intracerebral

(multiple metastases)

NA

NA

Eccrine adenocarcinoma

Chemo

Chemo (3 regimens);

WBRT (20 Gy), Chemo

35 months; 5 months; NA

84 months

Distant

Dead

Veillon [18]

1996

61

Female

Ethmoid sinus

8 × 5

-

Epidural

-

6 months

Adenoid cystic carcinoma (cylindroma)

Res

-

-

6 months

-

Alive

Wyld [27]

1996

76

Female

Parietal

8

-

Epidural

SSS

3 months

(familial cylindromatosis)

Dermal cylindroma

Res with scalp and skull

-

-

23 years

-

Alive

Sigal [13]

1997

54

Female

Retroauricular

6 × 4.5

 + 

Subdural

SS

10 years

Eccrine porocarcinoma

Res, Neck dissection

RT (50 Gy to cervical region,

45 Gy to tumor site)

Chemo

NA; subsequent months

2.5 years

Local

Dead

Ritter [17]

1999

82

Male

Occipital

5 × 5.3

-

Epidural

SSS

4 years

Eccrine porocarcinoma

Res, RT (60 Gy)

-

-

1 year

-

Alive

Castro [28]

2000

39

Female

Parietal

NA

-

Epidural

-

2 years

Ceruminous adenoid cystic carcinoma

Res, RT (60 Gy)

-

-

1 year

-

Alive

Ohta [25]

2004

73

Female

Frontal

6 × 4.5 × 5.5

 + 

Subdural

SSS

 > 20 years

Microcystic adnexal carcinoma

palliative Res

-

NA

NA

Local, distant

Dead

Donovan [14]

2006

54

Female

Parietal

11 × 13 × 5

 + 

Epidural

SSS

43 years

Eccrine adenocarcinoma

Res with skull

-

NA

18 months

NA

Dead

Durairaj [20]

2006

70

Female

Orbital

NA

-

NA

NA

NA

Malignant hidradenoma

Res, Chemo, RT

-

 < 1 year

 < 1 year

Distant

Dead

Gildea [12]

2007

59

Male

Parietal

9 × 7.9

-

Intracerebral

SSS

30 years

(familial cylindromatosis)

Cylindroma

Res

-

NA

NA

NA

NA

Pedamallu [10]

2009

48

Female

Buccal

10 × 5

-

Intracerebral

-

-

Malignant eccrine spiradenoma

Res (partial)

-

NA

5 weeks

NA

Dead

Sheth [16]

2010

45

Female

Parietal

4.2 × 3.8

-

Intracerebral

(multiple metastases)

-

6 years

Eccrine mucinous carcinoma

Res, Chemo

Res, WBRT

2.5 years

8 years

Distant

Dead

Lee [22]

2010

50

Female

Fronto-parietal

3.3 × 5.4 × 4.8

-

Intracerebral

SSS

1 year

Low-grade hidradenocarcinoma

Res, WBRT (54 Gy)

-

-

3 years

-

Alive

Araujo [19]

2012

31

Female

Occipital

NA

 + 

Intracerebral

Conflu

4 months

Malignant chonrdoid syringoma

Res with dura, adjuvant therapy

-

-

NA

-

NA

Maiti [21]

2014

14

Female

Parietal

NA

-

Epidural; intracerebral

-

4 years

Malignant nodular hidradenoma

Res

2nd Res with skull;

3rd Res, RT (45 G)

6 months; 1 year; 1 year

2 years 6 months

Local

Alive

Maiti [21]

2014

45

Female

Parietal

NA

-

Intracerebral

-

6 months

Malignant nodular hidradenoma

Res with skull, RT

-

 < 3 months

 < 3 months

NA

Dead

Jagannatha [23]

2016

76

Male

Parietal

7 × 5 × 4; 6 × 5 × 3

 + 

Intracerebral

SSS

14 years

Clear cell hidradenocarcinoma

Res with scalp, skull and dura,

WBRT

-

-

24 months

-

Alive

Shen [11]

2019

37

Male

Occipital

3.3 × 1.8

-

Skull; subdural

-; SS

-

Eccrine porocarcinoma

Res with skull

Res with skull and dura, RT

7 months; 1 year

1 year 7 months

Distant

Alive