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Table 1 Comparisons of demographic and clinical characteristics between each patient subgroup and healthy controls

From: Brain structural and functional connectivity alterations are associated with fatigue in neuromyelitis optica spectrum disorder

Characteristic

Healthy controls

(n = 20)

Low fatigue

(n = 17)

High fatigue

(n = 16)

p

Age, yr

45.2 ± 9.5

42.2 ± 11.8

47.1 ± 10.0

0.404

Female, n (%)

20(100%)

15(88.2%)

16(100%)

0.111

Years of education

9.0 ± 2.7

9.9 ± 3.5

8.6 ± 3.3

0.467

EDSS score

–

3.5 (1.5,4)

3.3 (2.3,4)

0.637

Disease duration, yr

–

6.7 (4.3,9.8)

3.3 (2.4,7.3)

0.081

HAMA score

0 (0,2.5)

5 (2,7)

7.5 (4.5,12.5)

0.000

HRSD score

0 (0,1.5)

2 (1,7)

9.5 (5,14.5)

0.000

Global FIS score

0 (0,0)

20 (13,39)

71.5 (58,108.5)

0.000

  1. Values are mean ± SD or median (interquartile range), unless otherwise noted
  2. yr years, EDSS Expanded Disability Status, HAMA Hamilton Anxiety Rating Scale, HRSD Hamilton Rating Scale for Depression, FIS Fatigue Impact Scale