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Table 4 Brain regions with significantly decreased functional connectivity in NMOSD patients with high fatigue compared to patients with low fatigue

From: Brain structural and functional connectivity alterations are associated with fatigue in neuromyelitis optica spectrum disorder

 

Seed ROIs

Brain regions

Peak MNI

Cluster voxels

Peak z value

X

Y

Z

Analysis 1*

Left pallidum

Left cerebellum posterior lobe

−39

−57

−36

38

−4.5611

  

Right cerebellum posterior lobe

30

−63

−36

42

−4.8523

Analysis 2#

Left pallidum

Left cerebellum posterior lobe

−39

−57

−36

33

−4.3456

  

Right cerebellum posterior lobe

30

−63

−36

34

−4.7087

  1. NMOSD neuromyelitis optica spectrum disorder, ROIs regions of interest, MNI Montreal Neurological Institute
  2. *, with FD_Jenkinson as covariate; #, with FD_Jenkinson, age, sex, years of education and scores on the HAMA and HRSD as covariates