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Table 1 Baseline characteristics of the participants according to median of the glucose-to-HbA1c ratio

From: Stress hyperglycemia is predictive of clinical outcomes in patients with spontaneous intracerebral hemorrhage

 

Overall(n = 586)

glucose-to-HbA1c ratio

P value

<1.02(n = 293)

≥1.02(n = 293)

Male, n (%)

412 (70.3)

209 (71.3)

203 (69.2)

0.59

Age (years)

58.5 ± 13.2

56.9 ± 12.7

60.1 ± 13.5

<0.01

Current smoking, n (%)

207 (35.3)

97 (33.1)

110 (37.5)

0.12

Alcohol consumption, n (%)

252 (43.0)

126 (43.0)

126 (43.0)

0.42

Hypertension, n (%)

560 (95.6)

276 (94.2)

284 (96.9)

0.11

Diabetes mellitus, n (%)

144 (24.6)

58 (19.8)

86 (29.4)

<0.01

Dyslipidemia, n (%)

218 (37.2)

117 (39.9)

101 (34.5)

0.17

History of cerebral infarction, n (%)

96 (16.4)

46 (15.7)

50 (17.1)

0.66

Prior antidiabetic agents, n (%)

75 (12.8)

29 (9.9)

46 (15.7)

0.1

SBP (mmHg)

163.0(150.0–181.0)

160.0 (148.0–177.0)

168.0 (150.0–188.0)

<0.001

DBP (mmHg)

96.0 (83.0–107.0)

95..0 (84.0–105.0)

98.0 (83.0–109.0)

0.21

GCS score

14.0 (12.0–15.0)

15.0 (13.0–15.0)

14.0 (11.0–15.0)

<0.001

NIHSS score

9.0 (3.0–15.0)

7.0 (3.0–13.0)

10.0 (3.0–16.0)

<0.001

Location of hematoma, n (%)

   

<0.01

 lobar

102 (17.4)

49 (16.7)

53 (18.1)

 

 deep

363 (62.0)

199 (67.9)

164 (56.0)

 

 infratentorial

50 (8.5)

20 (6.8)

30 (10.2)

 

Hematoma volume (ml)

13.0 (5.5–29.4)

10.0 (4.5–21.2)

18.7 (7.4–36.5)

<0.001

intraventricular extension, n (%)

176 (30.0)

59 (20.1)

117 (39.9)

<0.001

eGFR (ml/min)

54.7 (51.1–58.2)

55 .0 (51.6–58.3)

54.3 (50.4–58.0)

0.08

FBG (mmol/l)

5.8 (4.9–7.1)

4.9 (4.4–5.4)

6.8 (6.0–8.2)

<0.001

HbA1c (%)

5.6 (5.3–6.1)

5.6 (5.3–6.1)

5.6 (5.2–6.2)

0.86

hsCRP (mg/l)

8.7 (4.6–8.7)

8.7 (2.8–8.7)

8.7 (8.7–11.1)

<0.001

Post-stroke treatment of hyperglycemia, n (%)

114 (19.5)

41 (14.0)

73 (24.9)

<0.01

Surgery, n (%)

86 (14.7)

14 (4.8)

72 (24.6)

<0.001

Poor functional outcome at discharge, n (%)

292 (49.8)

100 (34.1)

192 (65.5)

<0.001

Poor functional outcome at 90 days, n (%)

256 (43.7)

85 (29.0)

171 (58.4)

<0.001

  1. Continuous variables are expressed as means ± (SD) or medians (IQR)
  2. SBP systolic blood pressure, DBP diastolic blood pressure, GCS Glasgow Coma Scale, NIHSS National Institutes of Health Stroke Scale, eGFR estimated glomerular filtration rate, FBG fasting blood glucose, HbA1c Glycated hemoglobin, hsCRP high-sensitivity C-reactive protein