Table 1 The spectrum of symptoms in anti-DPPX encephalitis
From: Anti-dipeptidyl-peptidase-like protein 6 encephalitis with pure cerebellar ataxia: a case report
Case | Age (years) | Sex | Symptoms: 1. Diarrhea or weight loss; 2. Hyperexcitability (myoclonus, tremor, spasticity, rigidity, stiffness, hyperekplexia; muscle cramps); 3. Cognitive dysfunction (memory loss, executive dysfunction); 4.Cerebellar ataxia (vertigo, ataxia, nystagmus, unsteady gait); 5. Psychiatric symptoms (agitation, paranoia, hallucinations, anxiety, mutism, depression); 6. Brainstem disorders (eye movement disturbances, dysphagia, dysarthria, respiratory failure); 7. Dysautonomia (constipation, thermoregulation, urine retention, tachycardia); 8. Sleep disorder; 9. Seizures; | Reference |
|---|---|---|---|---|
1 | 61 | Man | 1,2,3,5 | Boronat A et al. 2013 [3] |
2 | 45 | Female | 1,2,3,5,8,9 | Boronat A et al. 2013 [3] |
3 | 58 | Female | 2,4,5 | Boronat A et al. 2013 [3] |
5 | 15 | Man | 2,3,4 | Balint B et al. 2014 [6] |
6 | 27 | Man | 1,2,4,7 | Balint B et al. 2014 [6] |
7 | 26 | Man | 1,2,3,4,7 | Balint B et al. 2014 [6] |
8 | 18 | Man | 1,2,3,4,6,9 | Tobin WO et al [5]. 2014 |
9 | 57 | Man | 1,3,4,5,6,8 | Tobin WO et al [5]. 2014 |
10 | 37 | Female | 1,5,7,8 | Tobin WO et al [5]. 2014 |
11 | 36 | Female | 1,2,3,4,5,8 | Tobin WO et al. 2014 [5] |
12 | 51 | Female | 1,2,3,4,6,7 | Tobin WO et al. 2014 [5] |
13 | 75 | Man | 3,6,7 | Tobin WO et al. 2014 [5] |
14 | 61 | Man | 1,2,5,6 | Tobin WO et al. 2014 [5] |
15 | 70 | Man | 1,3,4,8 | Tobin WO et al. 2014 [5] |
16 | 63 | Man | 1,2,3,5,7,8 | Tobin WO et al. 2014 [5] |
17 | 39 | Female | 2,5 | Tobin WO et al. 2014 [5] |
18 | 52 | Female | 1,3 | Tobin WO et al. 2014 [5] |
19 | 66 | Man | 1,2,9 | Tobin WO et al. 2014 [5] |
20 | 24 | Man | 1,2,3,4,5,6,7,8 | Tobin WO et al. 2014 [5] |
21 | 13 | Female | 6,8 | Tobin WO et al. 2014 [5] |
22 | 49 | Man | 1,2,6,8 | Tobin WO et al. 2014 [5] |
23 | 53 | Female | 3,4,5 | Tobin WO et al. 2014 [5] |
24 | 55 | Man | 1,2,3,4,5,8 | Tobin WO et al. 2014 [5] |
25 | 46 | Man | 2,3,4,6 | Tobin WO et al. 2014 [5] |
24 | 40 | Female | 1,2,3,4 | Stoeck K et al. 2015 [7] |
26 | 52 | Man | 1,2,3,5 | Stokin GB et al. 2015 [7] |
27 | 36 | Female | 1,2,3,4,5,6 | Hara M et al. 2017 [4] |
28 | 52 | Man | 1,2,3,5,9 | Hara M et al. 2017 [4] |
29 | 68 | Man | 1,2,3,4,8 | Hara M et al. 2017 [4] |
30 | 67 | Man | 1,2,3,5,8,9 | Hara M et al [4]. 2017 |
31 | 49 | Man | 1,2,3,5 | Hara M et al [4]. 2017 |
32 | 57 | Man | 1,2,3,4,5 | Hara M et al. 2017 [4] |
33 | 45 | Female | 1,2,4,5,7 | Hara M et al. 2017 [4] |
34 | 57 | Man | 1,2,3,4,5,7 | Hara M et al. 2017 [4] |
35 | 69 | Man | 1,5 | Hara M et al. 2017 [4] |
36 | 72 | Man | 1,3,5,8 | Zhou Q et al. 2020 [10] |
37 | 77 | Man | 1,2,3,4,5,8 | Deuel LM et al. 2020 [9] |
38 | 53 | Man | 1,2,3,4,5,8 | Ye L et al. 2020 [11] |
39 | 44 | Female | 1,2,3,4,5,8 | Mbonde AA et al. 2021 [8] |
40 | 54 | Man | 1,2,3,4,5,7,8 | Mbonde AA et al. 2021 [8] |