Table 1 Demographic and clinical characteristics of the studied subjects

n

19

36

22

Sex, m/f

11/8

23/13

14/8

Age at death, years

55.9 (18) [19]

79.4 (6.2) [36]

79.1 (5.8) [22]

Height, cm

171.8 (9.7) [19]

169.3 (9.0) [36]

169.0 (9.6) [22]

Weight, kg

84.9 (18) [19]

68.9 (15.9) [36]

66.2 (15.9) [22]

Brain weight, g

-

1433 (153) [35]

1420 (169) [22]

Parkinsonism onset to death, years

-

8.4 (5.1) [25]

9.2 (5.0) [20]

Diagnosis to death, years

-

4.3 [6] [29]

6.6 [7] [20]

LEDD¹, mg

-

455 (372) [32]

520 (334) [21]

Hoehn and Yahr stage

-

4.1 (0.83) [26]

4.1 (0.85) [19]

SNc area, mm²

30.6 (5.9) [19]

31.9 (7.3) [36]

31.9 (7.2) [22]

SNc neuron count, n

121 (43.6) [19]

69.2 (41.5) [36]

63.2 (38.0) [22]

SNc neuron density, n/mm²

3.94 (1.21) [19]

2.17 (1.23) [36]

1.99 (1.17) [22]