Table 2 Intracranial lesion volume in particular regions in patients with and without diffuse spinal cord lesions
From: Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis
Patients without DL | Patients with DL | Statistical comparison (Mann-Whitney U-test) | ||
|---|---|---|---|---|
n (%) | 34 (29.4) | 24 (41.3) | p-value | p-value after FDR correction |
Total intracranial lesion volume (cm3) | 6.0 ± 8.1 | 10.1 ± 11.0 | 0.024 | 0.064 |
Frontal lesion volume (cm3) | 1.1 ± 1.7 | 2.0 ± 2.8 | 0.165 | 0.165 |
Temporal lesion volume (cm3) | 0.5 ± 1.1 | 1.1 ± 1.6 | 0.122 | 0.14 |
Parietal lesion volume (cm3) | 1.1 ± 2.0 | 2.3 ± 3.6 | 0.065 | 0.104 |
Occipital lesion volume (cm3) | 0.4 ± 0.4 | 0.7 ± 0.8 | 0.067 | 0.09 |
Deep hemispheric lesion volume (cm3) | 2.8 ± 3.6 | 3.8 ± 2.7 | .018 | 0.072 |
Cerebellar lesion volume (cm3) | 0.01 ± 0.05 | 0.05 ± 0.13 | 0.025 | 0.05 |
Brainstem lesion volume (cm3) | 0.01 ± 0.03 | 0.1 ± 0.15 | 0.001 | 0.008 |
n with- / n without infratentorial lesions | 17 / 17 | 20 / 4 | ||