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Table 3 Hierarchical binary logistic regression analysis investigating the relative contributions of covariates in predicting the presence of diffuse SC abnormalities

From: Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis

 

Model 1

Model 2

Model 3

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

Sex (female = reference)

1.76

0.51–6.11

.372

2.05

0.57–7.41

.271

2.12

0.42–10.79

.276

Age

0.96

0.89–1.04

.333

0.96

0.88–1.04

.276

.94

0.85–1.04

.284

Disease duration

1.05

0.67–1.64

.835

1.02

0.65–1.6

.938

1.43

0.78–2.63

.153

Intracranial lesion volume

 

1.06

0.99–1.13

.103

1.02

0.94–1.11

.606

Presence of brainstem lesions

 

47.10

6.9–321.61

<.001

Presence of cerebellar lesions

0.29

0.04–2.47

.259

Hosmer and Lemeshow chi2/p

3.07 / 0.93

7.81 / 0.45

3.54 / 0.9

Chi2 /Signif. of the step (model)

1.69 /0.69 (0.64)

4.95 / 0.071 (0.29)

35.01 / 0.001 (0.001)

Nagelkerke R2 for the model

0.04

0.11

0.55

  1. Dependent variable: presence of diffuse spinal cord abnormalities. CI Confidence interval, OR Odds ratio; p = level of significance. Hosmer–Lemeshow statistics indicate a poor fit if the significance value is less than 0.05