Table 4 Pairwise comparisons between healthy controls, patients with and without DL (with post hoc corrections)
From: Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis
Healthy controls (1) | Patients without DL (2) | Patients with DL (3) | Statistical comparison Mean difference (corresponding p-value) | Post-hoc pairwise comparison | |||
|---|---|---|---|---|---|---|---|
n | 58 | 34 | 24 | 1 vs. 2 | 1 vs. 3 | 2 vs. 3 | |
MUCCA (mm2) | 89.3 ± 7.9 | 88.8 ± 7.62 | 88.5 ± 11.6 | 0.4 (.974) | 0.8 (0.932) | 0.3 (0.988) | 1 |
MUCCA (%) | 0.0624 ± 0.006 | 0.0623 ± 0.007 | 0.0627 ± 0.008 | 0.00009 (0.998) | − 0.00033 (0.997) | −0.00042 (0.968) | 1 |
Brain volume (%) | 80.3 ± 2.0 | 79.0 ± 2.9 | 79.3 ± 3.3 | 1.3 (0.062) | 1.0 (0.272) | − 0.3 (0.897) | 2 |
GM (%) | 49.2 ± 2.1 | 48.6 ± 1.9 | 48.1 ± 2.4 | 0.6 (0.383) | 1.0 (0.103) | 0.4 (0.705) | 1 |
WM (%) | 31.2 ± 1.6 | 3.5 ± 1.9 | 31.2 ± 3.1 | 0.7 (0.283) | − 0.1 (0.989) | − 0.8 (0.362) | 1 |
Lat. ventricles (%) | 1.13 ± 0.58 | 1.35 ± .52 | 1.31 ± 0.77 | − 0.2 (0.228) | − 0.2 (0.426) | 0.03 (.978) | 2 |
Brainstem (%) | 2.2 ± 0.1 | 2.2 ± 0.1 | 2.2 ± 0.2 | 0.02 (0.823) | 0.01 (0.923) | −0.001 (0.99) | 1 |
Cerebellum (%) | 8.8 ± 0.7 | 9.0 ± 0.5 | 8.8 ± 0.6 | − 0.2 (0.497) | − 0.01 (0.998) | 0.14 (0.666) | 1 |
Corpus callosum (%) | 4.1 ± 0.5 | 3.9 ± 0.4 | 3.9 ± 0.6 | 0.2 (0.19) | 0.2 (0.367) | −0.02 (.981) | 1 |
Thalami (%) | 1.0 ± 0.1 | 1.0 ± 0.1 | 0.9 ± 0.2 | 0.002 (0.980) | 0.06 (0.002) | 0.05 (0.007) | 1 |