Table 3 Influencing factors of unfavorable outcomes in acute ischemic stroke using univariate regression analysis

HGB(g/dl), mean ± sd

13.510 ± 1.961

0.823 (0.780, 0.868)

 < 0.001

HCT(%),mean ± sd

40.177 ± 5.468

0.934 (0.916, 0.952)

 < 0.001

MCV(fl), mean ± sd

92.992 ± 5.215

0.985 (0.966, 1.005)

0.146

PLT(10^9/L), mean ± sd

224.648 ± 70.666

1.000 (0.998, 1.001)

0.736

TC(mg/dl), mean ± sd

179.853 ± 43.085

0.996 (0.994, 0.999)

0.002

TG(mg/dl), mean ± sd

107.344 ± 48.850

0.995 (0.993, 0.998)

 < 0.001

HDL-c(mg/dl), mean ± sd

47.040 ± 13.401

0.997 (0.989, 1.005)

0.467

LDL-c(mg/dl), mean ± sd

108.813 ± 37.292

0.998 (0.995, 1.001)

0.112

BUN(mg/dl),median (quartile)

16.000 (12.000–20.000)

1.014 (1.002, 1.027)

0.020

Scr(mg/dl),median (quartile)

0.890 (0.740–1.070)

0.992 (0.894, 1.101)

0.875

ALT(U/L),median (quartile)

23.000 (19.000–29.000)

1.007 (0.999, 1.014)

0.078

AST(U/L),median (quartile)

18.000 (13.000–26.000)

0.990 (0.982, 0.997)

0.008

ALB (g/dL), mean ± sd

4.029 ± 0.413

0.277 (0.213, 0.361)

 < 0.001

FBG(mmol/L), mean ± sd

5.920 ± 2.081

1.174 (1.118, 1.233)

 < 0.001

TG/HDL-c ratio,median (quartile)

2.128 (1.440–3.208)

0.932 (0.869, 0.999)

0.047

FIB (mg/L), mean ± sd

332.946 ± 82.970

1.003 (1.002, 1.004)

 < 0.001

BMI(kg/m²), mean ± sd

23.499 ± 3.233

0.920 (0.890, 0.951)

 < 0.001

Sex, n(%)

 Male

1073 (60.828%)

Ref

 Female

691 (39.172%)

1.747 (1.415, 2.156)

 < 0.001

Age(years), n(%)

 < 60

395 (22.39%)

Ref

 60 to < 70

466 (26.42%)

1.301 (0.927, 1.826)

0.128

 70 to < 80

629 (35.66%)

2.586 (1.931, 3.462)

 < 0.001

 ≥ 80

203 (11.51%

4.379 (3.085, 6.218)

 < 0.001

Hypertension, n(%)

 NO

648 (36.735%)

Ref

 Yes

1116 (63.265%)

1.376(1.103, 1.716)

0.005

DM, n(%)

 No

1213 (68.764%)

Ref

 Yes

551 (31.236%)

1.510 (1.213, 1.878)

 < 0.001

Previous stroke/TIA, n(%)

 No

1395 (79.082%)

Ref

 Yes

369 (20.918%)

1.764 (1.384, 2.248)

 < 0.001

NIHSS score, n(%)

 < 6

1209 (68.537%)

Ref

 6 to 13

352 (19.955%)

6.774 (5.193, 8.837)

 < 0.001

 ≥ 14

203 (11.508%)

17.026 (11.994, 24.170)

 < 0.001

CHD, n(%)

 No

1561 (88.492%)

Ref

 Yes

203 (11.508%)

0.974 (0.702, 1.350)

0.873

Stroke etiology, n(%)

 SVO

343 (19.444%)

Ref

 LAA

574 (32.540%)

1.659 (1.193, 2.306)

0.003

 CE

448 (25.397%)

2.351 (1.681, 3.289)

 < 0.001

 Other determined

148 (8.390%)

3.204 (2.093, 4.905)

 < 0.001

 Undetermined

251 (14.229%)

1.366 (0.916, 2.037)

0.126

Smoking, n(%)

 No

1063 (60.261%)

Ref

 Yes

701 (39.739%)

0.604 (0.484, 0.752)

 < 0.001