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Table 1 Demographic and clinical characteristics of the study population

From: Reduced brain subcortical volumes in patients with glaucoma: a pilot neuroimaging study using the region-of-interest-based approach

Characteristics

Individuals with glaucoma (N = 64)

Individuals without glaucoma (N = 128)

pa

Age (years)

70.97 ± 5.37

70.57 ± 5.32

0.63

Sex

 Male

26 (40.6)

52 (40.6)

1.00

 Female

38 (59.4)

76 (59.4)

 

Education level

  < middle school

39 (60.9)

78 (60.9)

1.00

  ≥ middle school

25 (39.1)

50 (39.1)

 

Marital status

 Married

51 (79.7)

97 (76.4)

0.61

 Non-married

13 (20.3)

30 (23.6)

 

Hypertension

 Yes

50 (78.1)

48 (37.5)

< 0.001

 No

14 (21.9)

80 (62.5)

 

Angina or myocardial infarction

 Yes

9 (14.1)

15 (11.7)

0.64

 No

55 (85.9)

113 (88.3)

 

Diabetes mellitus

 Yes

27 (42.2)

23 (18.0)

< 0.001

 No

37 (57.8)

105 (82.0)

 

Smoking status

 Current smoker

3 (4.7)

3 (2.3)

0.54

 Former smoker

20 (31.3)

35 (27.3)

 

 Never smoker

41 (64.1)

90 (70.3)

 

Alcohol consumption

 Yes

33 (51.6)

71 (55.9)

0.57

 No

31 (48.4)

56 (44.1)

 

Body mass index (kg/m2)

  < 18.5

0 (0.0)

1 (0.8)

0.68

 18.5-22.9

18 (28.1)

33 (25.8)

 

 23.0-24.9

21 (32.8)

35 (27.3)

 

  ≥ 25.0

25 (39.1)

59 (46.1)

 

Systolic blood pressure (mmHg)

  < 120

19 (29.7)

31 (24.2)

0.74

 120-139

28 (43.8)

62 (48.4)

 

 140-159

15 (23.4)

28 (21.9)

 

  ≥ 160

2 (3.1)

7 (5.5)

 

Diastolic blood pressure (mmHg)

  < 80

48 (75.0)

84 (65.6)

0.23

 80-90

15 (23.4)

35 (27.3)

 

 90-100

0 (0.0)

7 (5.5)

 

  ≥ 100

1 (1.6)

2 (1.6)

 

Fasting blood glucose (mg/dL), mean (standard deviation)

109.94 ± 34.23

99.34 ± 20.66

0.008

Total cholesterol (mg/dL), mean (standard deviation)

186.23 ± 38.56

177.90 ± 33.44

0.13

  1. a Significance of difference between individuals with and without glaucoma; Chi-squared tests for categorical variables and paired t-tests for continuous variables were used.