BMC Neurology

Table 4 Cortical thickness and subcortical volume in individuals with glaucoma compared to age, sex, and educational level-matched individuals without glaucoma

From: Reduced brain subcortical volumes in patients with glaucoma: a pilot neuroimaging study using the region-of-interest-based approach

		Unadjusted model			Adjusted model
		Beta	Standard error	p^*	Beta	Standard error	p^*
Cortical thickness (mm)	Global	−0.020	0.012	0.20	−0.011	0.014	0.75
	Frontal lobe	−0.015	0.015	0.46	−0.007	0.018	0.94
	Parietal lobe	−0.035	0.015	0.070	−0.021	0.017	0.67
	Temporal lobe	−0.024	0.015	0.20	−0.016	0.018	0.67
	Occipital lobe	−0.040	0.013	0.014	−0.016	0.015	0.67
	Cingulate	−0.011	0.018	0.62	−0.003	0.022	0.94
	Insula	0.004	0.021	0.86	0.002	0.024	0.94
Subcortical volume (mm³)	Thalamus	−300.45	73.97	0.004	−212.81	88.03	0.028
	Caudate	−187.61	63.20	0.007	−170.03	73.73	0.029
	Putamen	− 126.91	63.99	0.055	−151.41	75.03	0.051
	Pallidum	−87.45	26.36	0.004	−103.59	31.26	0.007
	Hippocampus	−110.42	47.58	0.028	−141.37	55.94	0.026
	Amygdala	−75.44	26.58	0.009	−87.94	31.42	0.018
	Nucleus accumbens	−16.32	10.17	0.11	−20.44	11.60	0.078

Footnotes. The adjusted model included the history of disease (hypertension, angina or myocardial infarction, and diabetes mellitus), lifestyle factors (smoking status and current alcohol consumption status), marital status, systolic blood pressure, diastolic blood pressure, body mass index, total cholesterol level, fasting blood glucose level, and intracranial volume. ^* P-values were corrected for multiple comparisons using the false discovery rate method

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ISSN: 1471-2377

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