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Fig. 3 | BMC Neurology

Fig. 3

From: Clinical characteristics and proteome modifications in two Charcot-Marie-Tooth families with the AARS1 Arg326Trp mutation

Fig. 3

Proteome analysis. Label-free, quantitative proteome analysis of AARS1 patient PBMC cells compared to healthy controls. A Principal component analysis shows clear separation of AlaRS patient proteome compared to healthy controls. B Volcano plot showing the 457 statistically significant differences in the proteomes (t-test, q < 0.05 and p < 0.05), ten most up- and downregulated proteins marked to the right and left, respectively

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