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Table 1 Basic information of patients with anterior circulation stroke in ESUS, CE, and LAA

From: Characteristics of non-stenotic carotid plaque in embolic stroke of undetermined source compared with cardiogenic embolism: a retrospective cross-sectional observational study

Characteristics

nCE (n = 37)

ESUS (n = 81)

P-value

LAA (n = 162)

ESUS (n = 81)

P-value

Gender male, n (%)

22 (59.46)

51 (62.96)

0.716a

101 (62.35)

51 (62.96)

0.925a

Age, years, median (IQR)

74.0 (64.0–82.5)

65.0 (56.0–72.5)

0.001b

67.0 (57.8–74.0)

65.0 (56.0–72.5)

0.302b

Smoking, n (%)

7 (18.92)

33 (40.74)

0.020a

56 (34.57)

33 (40.74)

0.346a

Diabetes Mellitus, n (%)

10 (27.03)

31 (38.27)

0.234a

72 (44.44)

31 (38.27)

0.359a

Hypertension, n (%)

22 (59.46)

67 (82.72)

0.006a

141 (87.04)

67 (82.72)

0.366a

Homocysteine, μmol/L, mean ± SD

10.97 ± 3.48

11.74 ± 7.09

0.534c

11.25 ± 6.32

11.74 ± 7.09

0.588c

Triglyceride, mmol/L, mean ± SD

1.03 ± 0.55

1.56 ± 0.90

< 0.001c

1.56 ± 1.01

1.56 ± 0.90

0.996c

Lipoprotein (a), g/L, mean ± SD

0.25 ± 0.19

0.27 ± 0.24

0.661c

0.32 ± 0.28

0.27 ± 0.24

0.165c

Total cholesterol, mmol/L, mean ± SD

3.81 ± 0.68

4.21 ± 0.99

0.027c

4.06 ± 0.93

4.21 ± 0.99

0.262c

High density lipoprotein cholesterol, mmol/L, mean ± SD

1.15 ± 0.31

1.07 ± 0.22

0.177c

1.05 ± 0.26

1.07 ± 0.22

0.597c

Low density lipoprotein cholesterol, mmol/L, mean ± SD

2.24 ± 0.59

2.55 ± 0.81

0.044c

2.46 ± 0.76

2.55 ± 0.81

0.425c

NIHSS score, median (IQR)

4.0 (3.0–5.0)

3.0 (1.0–5.0)

0.107b

3.5 (2.0–6.0)

3.0 (1.0–5.0)

0.095b

With intracranial plaque ipsilateral to the stroke site, n (%)

5 (13.51)

13 (16.05)

0.722a

_

13 (16.05)

_

  1. aPearson’s χ2 test
  2. bMann–Whitney U-test
  3. cStudent’s t-test
  4. Abbreviations: ESUS Embolic stroke of undetermined source, LAA Large-artery atherosclerosis, CE Cardiogenic embolism, NIHSS National Institutes of Health Stroke Scale, IQR Interquartile range, SD Standard deviation