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Table 4 Relationship between dynamic NLR and mortality in 237 patients at 1 month using a generalized additive mixed model

From: Prolonged increased neutrophil-to-lymphocyte ratio is associated with mortality after successful revascularization for treatment of acute ischemic stroke

Outcome

Model Ia

Model IIb

β (95% CI)

P value

β (95% CI)

P value

Interceptc

9.086 (8.499, 9.673)

< 0.001

4.381 (1.230, 7.559)

0.007

Dayd

−0.237 (−0.272, − 0.202)

< 0.001

−0.244 (− 0.279, − 0.208)

< 0.001

Deathe

2.850 (1.391, 4.301)

< 0.001

1.243 (− 0.708, 3.1940)

0.213

Day × deathf

0.288 (0.182, 0.394)

< 0.001

0.293 (0.186, 0.400)

< 0.001

  1. CI Confidence interval, NLR Neutrophil-to-lymphocyte ratio
  2. aModel I: not adjusted for other covariates
  3. bModel II: adjusted for sex; age; history of diabetes; history of chronic kidney disease; baseline NIHSS score; bridging intravenous thrombolysis; cardioembolic stroke; internal carotid artery occlusion; favorable collateral circulation; pneumonia during hospitalization; symptomatic intracerebral hemorrhage during hospitalization; sepsis during hospitalization; anticoagulation during hospitalization; use of invasive mechanical ventilation during hospitalization; use of vasopressors during hospitalization
  4. cIntercept: the mean NLR at day = 0 and death = 0
  5. dDay: the mean decrease in NLR at death = 0 over time (daily)
  6. eDeath: the difference in NLR at day = 0 between nonsurvivors = 1 and survivors = 0
  7. fDay × death: the mean decrease in NLR daily under the condition of nonsurvivors = 1 and survivors = 0
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BMC Neurology

ISSN: 1471-2377

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