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Table 2 Retina structural data of MOGAD-ON eyes in comparison to AQP4-Ab-ON eyes and HC

From: The difference of the retinal structural and microvascular characteristics in patients with MOGAD-ON and AQP4-ON

 

MOG-ON

AQP4-ON

HC

MOG-ON VS. AQP4-ON

MOG-ON VS. HC

 

Eye = 26

Eye = 40

Eye = 60

B

SE

p

B

SE

p

pRNFL (um)

75.49 (17.98)

78.69 (18.59)

119.74 (10.08)

−0.015

0.016

0.350

−0.238

0.071

0.001*

TEM-RNFL (um)

49.80 (16.90)

55.37 (14.78)

84.03 (9.38)

−0.020

0.019

0.310

−0.163

0.039

0.000*

SUP-RNFL (um)

92.84 (24.56)

96.56 (29.42)

146.31 (14.71)

−0.010

0.010

0.317

−0.305

0.117

0.009*

NAS-RNFL (um)

65.48 (14.25)

64.88 (14.25)

96.03 (15.68)

−0.003

0.019

0.857

−0.134

0.031

0.000*

INF-RNFL (um)

93.01 (28.18)

97.79 (29.26)

152.58 (17.51)

−0.008

0.010

0.392

−0.103

0.025

0.000*

GCC (um)

74.71 (10.19)

74.28 (13.70)

99.12 (5.07)

−0.013

0.022

0.555

−0.029

0.018

0.000*

Outer Retina (um)

172.21 (6.63)

175.67 (8.82)

175.62 (7.55)

−0.058

0.039

0.137

−0.184

0.029

0.062

  1. AQP4-ON Aquaporin4-IgG seropositive optical neuritis, B Beta, GCC Ganglion cell complex, also refer to the inner retina, HC Health controls, INF Inferior quadrant, MOGAD-ON MOG-Ab-associated disease optical neuritis, NAS Nasal quadrant, pRNFL peri-papillary retinal nerve fiber layer, SUP Superior quadrant, SE Standard error, TEM Temporal quadrant, * p<0.05