A—Possible SN if score > 6,5 | |
(a) Ataxia in the lower or upper limbs at onset or full development | 3.1 |
(b) Asymmetrical distribution of sensory loss at onset or full development | 1.7 |
(c) Sensory loss not restricted to the lower limbs at full development | 2.0 |
(d) At least 1 SNAP absent or 3 SNAP < 30% of the lower limit of normal in the upper limbs, entrapment neuropathies excluded | 2.8 |
(e) < 2 nerves with abnormal motor nerve conduction studies in the lower limbs | 3.1 |
B—Probable SN if score > 6,5 AND (a) AND ((b) or (c)) | |
(a) The initial workup does not show biochemical or electrophysiological findings excluding SN | |
(b) The patient has one of the following: i. diagnosis of cancer within 5 years ii. cisplatin treatment iii. Detection of onconeural AB iv. diagnosis of an HIV infection v. Sjögren’s syndrome | |
(c) MRI shows T2-hyperintensity in the posterior column of the spinal cord | |
C—Definite SN pathological demonstration of dorsal root ganglia degeneration trough biopsy |