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Table 1 Sample characteristics

From: The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia

 

DLB

(n = 92)

PDD

(n = 93)

x2/Z-score

P-value

Gender, n (%)

  

0.046

0.830

 Male

50 (54.3%)

52 (55.9%)

  

 Female

42 (45.7%)

41 (44.1%)

  

Age at visit, years, median (IQR)

71 (66,78)

67 (62,74)

−3.900

0.000

Age at onset, years, median (IQR)

69 (63,75)

63 (59,71)

−3.456

0.001

Education, years, median (IQR)

9 (9,15)

9 (6,12)

−2.142

0.032

Marital status, n (%)

  

0.144

0.705

 Married

67 (72.8%)

70 (75.3%)

  

 Widowed

20 (21.7%)

23 (24.7%)

  

 Divorced

1 (1.1%)

0 (0.0%)

  

 Single

4 (4.3%)

0 (0.0%)

  

Smoking, yes, n (%)

25 (27.2%)

20 (21.5%)

0.807

0.369

Alcohol consumption, yes, n (%)

20 (21.7%)

15 (16.1%)

0.949

0.330

Cardiometabolic conditions, n (%)

 Heart disease

21 (22.8%)

31 (33.3%)

2.527

0.112

 Hypertension

30 (32.6%)

16 (17.2%)

5.874

0.015

 DM

22 (23.9%)

10 (10.8%)

5.599

0.018

 Stroke

12 (13.0%)

8 (8.6%)

0.946

0.331

APOE genotype frequency, n (%)

 2/2

1 (1.1%)

2 (2.2%)

0.328

1.000

 2/3

3 (3.3%)

8 (8.6%)

2.359

0.212

 2/4

0 (0.0%)

1 (1.1%)

0.995

1.000

 3/3

35 (38. 0%)

71 (76.3%)

27.728

0.000

 3/4

51 (55.4%)

10 (10.8%)

41.779

0.000

 4/4

2 (2.2%)

1 (1.1%)

0.350

0.621

APOE allele frequency, n (%)

 ε2

5 (2.7%)

13 (7.0%)

3.647

0.056

 ε3

124 (67. 4%)

160 (86.0%)

17.995

0.000

 ε4

55 (29.9%)

13 (7.0%)

32.342

0.000

APOE ε4 carriers, n (%)

  

40.557

0.000

 Yes

53 (57.6%)

12 (12.9%)

  

 No

39 (42.4%)

81 (87.1%)

  

Drug prescriptions, n (%)

 ChEIs

63 (68.5%)

9 (9.7%)

67.266

0.000

 Anti-Parkinsonism

11 (12.0%)

50 (53.8%)

36.575

0.000

 Antipsychotics

18 (19.6%)

3 (3.2%)

12.270

0.000

Core features, n (%)

 FLC

26 (28.3%)

9 (9.7%)

10.412

0.001

 VH

44 (47.8%)

13 (14.0%)

24.855

0.000

 Parkinsonism

44 (47.8%)

93 (100.0%)

54.914

0.000

 RBD

51 (55.4%)

21 (22.6%)

21.000

0.000

  1. Abbreviations: DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, IQR Interquartile range, DM Diabetes mellitus, APOE Apolipoprotein E, ChEIs Cholinesterase inhibitors, FLC Fluctuating cognition, VH Visual hallucination, RBD Rapid eye movement sleep behavior disorder